Retention, Bacterial Adhesion, and Biofilm Formation between Anionic and Zwitterionic Bandage Contact Lenses in Healthy Dogs: A Pilot Study

被引：0

作者：

Kita, Mizuki ^{[1
]}

Kanai, Kazutaka ^{[1
]}

Ono, Hisaya K. ^{[2
]}

Otaka, Yuya ^{[1
]}

Okada, Daiki ^{[1
]}

Nagai, Noriaki ^{[3
]}

Kudo, Rina ^{[1
]}

Yamashita, Yohei ^{[1
]}

Hino, Shiori ^{[4
]}

Matsunaga, Toru ^{[4
]}

Tajima, Kazuki ^{[1
]}

机构：

[1] Kitasato Univ, Sch Vet Med, Dept Small Anim Internal Med 2, 35-1 Higashi 23 Ban Cho, Towada, Aomori 0348628, Japan

[2] Kitasato Univ, Sch Vet Med, Dept Zoonoses, 35-1 Higashi 23 Ban Cho, Towada, Aomori 0348628, Japan

[3] Kindai Univ, Fac Pharm, 3-4-1 Kowakae, Higashiosaka, Osaka 5778502, Japan

[4] Seed Co Ltd, Bunkyo Ku, 2-40-2 Hongo, Tokyo 1138402, Japan

来源：

VETERINARY SCIENCES | 2021年 / 8卷 / 10期

关键词：

bacterial adhesion; bandage contact lens; biofilm formation; contact lens retention; dogs; CORNEAL EPITHELIAL DEFECTS; SURFACE-CHARGE; KERATITIS; MODEL; HYDROPHOBICITY; GROWTH; SCCEDS;

D O I：

10.3390/vetsci8100238

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

This study aimed to compare the in vitro and in vivo retention, bacterial adhesion, and biofilm formation between anionic and zwitterionic bandage contact lenses (BCLs) in healthy canines. BCL retention and tolerance were evaluated in 10 healthy canines via a single-masked, crossover study for 7 days. To compare in vitro bacterial adhesion and biofilm formation, four Staphylococcus strains were incubated with the BCLs at 37 degrees C for 2 or 24 h, and the bacterial colony forming units (CFUs) adhering to the BCLs were counted. Next, to compare in vivo bacterial adhesion, the CFUs of bacteria adhering to the BCLs worn by canines for 24 h were counted. Anionic lenses significantly retained and reduced in vitro bacterial adhesion than in the zwitterionic lenses. However, the amount of in vitro biofilm formation was more likely to be higher on anionic lenses than on zwitterionic lenses. In vivo bacterial adhesion was not significantly different between the two types of BCLs. Nevertheless, both BCLs were well-tolerated by the canines; thus, their short-term use in dogs can be recommended as safe.

引用

页数：11

共 40 条

[1]

Al-Mujaini Abdullah, 2009, Sultan Qaboos Univ Med J, V9, P184

[2] Evaluation of Contact Lens Multipurpose Solutions on Bacterial Biofilm Development [J].