Longitudinal Cognitive Decline in Patients With Mild Cognitive Impairment or Dementia Due to Alzheimer's Disease

被引：11
作者：
Lim, Y. Y. [1 ]
Kong, J. [2 ]
Maruff, P. [3 ,4 ]
Jaeger, J. [5 ,6 ]
Huang, E. [2 ]
Ratti, E. [2 ]
机构：
[1] Monash Univ, Sch Psychol Sci, Turner Inst Brain & Mental Hlth, Clayton, Vic, Australia
[2] Biogen, Cambridge, MA USA
[3] Univ Melbourne, Florey Inst Neurosci & Mental Hlth, Parkville, Vic, Australia
[4] Cogstate Ltd, Melbourne, Vic, Australia
[5] CognitionMetrics Inc, Wilmington, DE USA
[6] Albert Einstein Coll Med, New York, NY USA
来源：
JPAD-JOURNAL OF PREVENTION OF ALZHEIMERS DISEASE | 2022年 / 9卷 / 01期
基金：
澳大利亚国家健康与医学研究理事会;
关键词：
Alzheimer's disease; mild cognitive impairment; Cogstate Brief Battery; International Shopping List Test; cognitive decline; COGSTATE BRIEF BATTERY; HEALTHY OLDER-ADULTS; A-BETA; MEMORY DECLINE; PERFORMANCE; BIOMARKERS; DESIGN; AIBL;
D O I：
10.14283/jpad.2021.64
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Sensitive cognitive assessments accurately detect and track cognitive decline in Alzheimer's disease. The Cogstate battery was used to measure cognitive change in cognitively normal participants and in individuals with mild cognitive impairment and mild Alzheimer's disease enrolled in the Australian Imaging, Biomarker and Lifestyle Rate of Change Substudy. Over 18 months, verbal episodic memory performance declined for mild cognitive impairment and mild Alzeheimer's disease groups when compared to cognitively normal participants. Frequent assessments of episodic memory may facilitate early detection of cognitive decline due to Alzheimer's disease.
引用
收藏
页码：178 / 183
页数：6
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