The importance of predictive biomarkers in oncology drug development

被引:11
作者
Jorgensen, Jan Trost [1 ]
机构
[1] Dx Rx Inst, Baunevaenget 76, DK-3480 Fredensborg, Denmark
关键词
Companion diagnostics; complementary diagnostics; personalized medicine; precision medicine; NSCLC; crizotinib; ceritinib; alectinib; ROS1; ALK; CELL LUNG-CANCER; CRIZOTINIB; RISK;
D O I
10.1080/14737159.2016.1199962
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
引用
收藏
页码:807 / 809
页数:3
相关论文
共 11 条
[1]   Second-line combination therapies in nonsmall cell lung cancer without known driver mutations [J].
Bluthgen, Maria-Virginia ;
Besse, Benjamin .
EUROPEAN RESPIRATORY REVIEW, 2015, 24 (138) :582-593
[2]   Biomarkers and Receptor Targeted Therapies Reduce Clinical Trial Risk in Non-Small-Cell Lung Cancer [J].
Falconi, Adam ;
Lopes, Gilberto ;
Parker, Jayson L. .
JOURNAL OF THORACIC ONCOLOGY, 2014, 9 (02) :163-169
[3]   Crizotinib for ALK-Rearranged Non-Small Cell Lung Cancer: A New Targeted Therapy for a New Target [J].
Gandhi, Leena ;
Jaenne, Pasi A. .
CLINICAL CANCER RESEARCH, 2012, 18 (14) :3737-3742
[4]   Clinical application of companion diagnostics [J].
Jorgensen, Jan Trost .
TRENDS IN MOLECULAR MEDICINE, 2015, 21 (07) :405-407
[5]   Where is personalized medicine in industry heading? [J].
Milne, Christopher-Paul ;
Cohen, Joshua P. ;
Chakravarthy, Ranjana .
NATURE REVIEWS DRUG DISCOVERY, 2015, 14 (12) :812-813
[6]  
Molecular Abbott, 2011, VYS ALK BREAK AP FIS
[7]  
Pfizer, U S PRESCR INF XALK
[8]   Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer [J].
Rikova, Klarisa ;
Guo, Ailan ;
Zeng, Qingfu ;
Possemato, Anthony ;
Yu, Jian ;
Haack, Herbert ;
Nardone, Julie ;
Lee, Kimberly ;
Reeves, Cynthia ;
Li, Yu ;
Hu, Yerong ;
Tan, Zhiping ;
Stokes, Matthew ;
Sullivan, Laura ;
Mitchell, Jeffrey ;
Wetzel, Randy ;
MacNeill, Joan ;
Ren, Jian Min ;
Yuan, Jin ;
Bakalarski, Corey E. ;
Villen, Judit ;
Kornhauser, Jon M. ;
Smith, Bradley ;
Li, Daiqiang ;
Zhou, Xinmin ;
Gygi, Steven P. ;
Gu, Ting-Lei ;
Polakiewicz, Roberto D. ;
Rush, John ;
Comb, Michael J. .
CELL, 2007, 131 (06) :1190-1203
[9]  
Rubinger DA, 2015, BIOMARK MED, V9, P13, DOI [10.2217/bmm.14.80, 10.2217/BMM.14.80]
[10]   Crizotinib in ROS1-Rearranged Non-Small-Cell Lung Cancer [J].
Shaw, Alice T. ;
Ou, Sai-Hong I. ;
Bang, Yung-Jue ;
Camidge, D. Ross ;
Solomon, Benjamin J. ;
Salgia, Ravi ;
Riely, Gregory J. ;
Varella-Garcia, Marileila ;
Shapiro, Geoffrey I. ;
Costa, Daniel B. ;
Doebele, Robert C. ;
Long Phi Le ;
Zheng, Zongli ;
Tan, Weiwei ;
Stephenson, Patricia ;
Shreeve, S. Martin ;
Tye, Lesley M. ;
Christensen, James G. ;
Wilner, Keith D. ;
Clark, Jeffrey W. ;
Iafrate, A. John .
NEW ENGLAND JOURNAL OF MEDICINE, 2014, 371 (21) :1963-1971