Primary hyperparathyroidism caused by an ectopic parathyroid adenoma in an uncommon location: a case report

被引:2
作者
Khalaf, Saeed H. [1 ]
Sarwani, Aysha A. [1 ]
George, Sara M. [2 ]
Al Saeed, Mahmood K. [3 ]
机构
[1] Salmaniya Med Complex, Dept Endocrinol, Manama, Bahrain
[2] Salmaniya Med Complex, Dept Pathol, Manama, Bahrain
[3] Salmaniya Med Complex, Dept Internal Med, Rd 2904, Manama, Bahrain
来源
JOURNAL OF TAIBAH UNIVERSITY MEDICAL SCIENCES | 2021年 / 16卷 / 05期
关键词
Ectopic parathyroid adenoma; Hypercalcemia; Hyperparathyroidism; Mediastinum; Parathyroid adenoma; LOCALIZATION;
D O I
10.1016/j.jtumed.2021.02.010
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Primary hyperparathyroidism caused by an ectopic parathyroid adenoma in the mediastinum is a rare clinical condition. We present a 75-year-old male with primary hyperparathyroidism caused by an ectopic parathyroid adenoma in the mediastinum. This patient was initially referred to the clinic for suspected incidental hypercalcemia. Initial imaging showed two suspicious lesions: one adjacent to the thyroid gland and another in the mediastinum. Further investigations identified a sole mediastinal adenoma. The diagnosis was confirmed by normalization of parathyroid hormone levels after its surgical resection. Thoroughly diagnosing such cases can prove challenging and using a single modality such as ultrasonography, computed tomography, or nuclear imaging alone may not yield conclusive findings or can give false positive results. Our case demonstrates that a combination of several imaging modalities can lead to accurate localization of the cause of primary hyperparathyroidism. This will obviate the performance of unnecessary surgical procedures. In addition, the possibility of missing additional sources of ectopic secretions of the parathyroid hormone will be reduced. (c) 2021 Taibah University. Production and hosting by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http:// creativecommons.org/licenses/by-nc-nd/4.0/).
引用
收藏
页码:782 / 787
页数:6
相关论文
共 50 条
  • [21] Ectopic parathyroid adenoma in the soft palate: a case report
    Brent A. Chang
    Anil Sharma
    Donald W. Anderson
    Journal of Otolaryngology - Head & Neck Surgery, 45
  • [22] A case of tuberous sclerosis complex with concomitant primary hyperparathyroidism due to parathyroid adenoma: a case report
    Yuji Shinzato
    Yasukazu Ikehara
    World Journal of Surgical Oncology, 13
  • [23] Ectopic parathyroid adenoma in the submandibular region: a case report
    Kong, Y.
    Ge, S. Y.
    Shang, W.
    Song, K.
    BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY, 2019, 57 (10) : 1150 - 1152
  • [24] A case of tuberous sclerosis complex with concomitant primary hyperparathyroidism due to parathyroid adenoma: a case report
    Shinzato, Yuji
    Ikehara, Yasukazu
    WORLD JOURNAL OF SURGICAL ONCOLOGY, 2015, 13
  • [25] Case report: a rare case of primary hyperparathyroidism due to an intrathymic ectopic parathyroid adenoma incidentally diagnosed in a 15-year-old girl
    Gurluler, Ercument
    FRONTIERS IN ENDOCRINOLOGY, 2024, 15
  • [26] Robotic transthoracic approach to ectopic mediastinal parathyroid adenoma: A case report
    Dowling, Gavin P.
    Hehir, Cian M.
    Daly, Gordon R.
    Shuhaibar, Maher N.
    Walshe, Peter
    INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, 2025, 126
  • [27] Brown tumor in a patient with ectopic mediastinal parathyroid adenoma: A case report
    Qari, Faiza A.
    SAUDI DENTAL JOURNAL, 2014, 26 (02) : 74 - 77
  • [28] Intrathymic ectopic parathyroid adenoma caused primary hyperparathyroidism with vitamin D deficiency several years after bariatric surgery
    Sellitri, Francesco
    Tamburrini, Alessandro
    Tacconi, Federico
    Bollero, Patrizio
    Ortensi, Andrea
    Mineo, Tommaso Claudio
    THORACIC CANCER, 2015, 6 (01) : 101 - 104
  • [29] Multimodality Evaluation of Persistent Hyperparathyroidism in a Rare Case of Ectopic Submandibular Parathyroid Adenoma
    Edamadaka, Yeshwanth
    Malhotra, Gaurav
    Daga, Aaditya
    Memon, Saba S.
    Lila, Anurag R.
    Bandgar, Tushar
    CLINICAL NUCLEAR MEDICINE, 2024, 49 (12) : E670 - E673
  • [30] A Case of Pregnancy Complicated by Primary Hyperparathyroidism Due to a Parathyroid Adenoma
    Mokrysheva, Natalia G.
    Eremkina, Anna K.
    Mirnaya, Svetlana S.
    Rozhinskaya, Lyudmila Y.
    Kuznetsov, Nikolay S.
    Yesayan, Rosa M.
    Kan, Natalia E.
    Dudinskaya, Ekaterina N.
    AMERICAN JOURNAL OF CASE REPORTS, 2019, 20 : 53 - 59