Salting-out crystallization of salts of β-lactam antibiotics

被引:0
|
作者
Savel'ev, EA [1 ]
Volkova, IM
机构
[1] Joint Stock Co, Res Technol Inst Antibiot & Enzymes Med Purposes, St Petersburg, Russia
[2] Biokhimik Joint Stock Co, Mordovia, Russia
关键词
Antibiotics;
D O I
暂无
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Recovery of a series of salts of beta -lactam antibiotics from aqueous, aqueous-alcoholic, and organic solvent solutions by salting-out crystallization is considered. It is shown that, with sodium salts of oxacillin, cloxacillin, and dicloxacillin, subtle differences in the chemical structure of molecules may lead to substantial difference in their behavior in salting-out crystallization.
引用
收藏
页码:1813 / 1818
页数:6
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