Genetic risk factors for chronic obstructive pulmonary disease

被引：31
作者：
Sandford, AJ
Paré, PD
机构：
[1] St Pauls Hosp, Ctr Hlth Evaluat & Outcomes Sci, Vancouver, BC V6Z 1Y6, Canada
[2] Univ British Columbia, Pulm Res Lab, Vancouver, BC V5Z 1M9, Canada
[3] Univ British Columbia, Dept Med, Vancouver, BC V5Z 1M9, Canada
来源：
CLINICS IN CHEST MEDICINE | 2000年 / 21卷 / 04期
关键词：
D O I：
10.1016/S0272-5231(05)70173-8
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
There is convincing epidemiologic evidence of genetic susceptibility to chronic obstructive pulmonary disease (COPD). Identification of susceptibility genes could yield important insights into the pathogenesis of COPD and may provide targets for therapeutic intervention. Deficiency of alpha(1)-antitrypsin is the only well-established genetic risk factor for COPD, but several other genes are implicated in the pathogenesis of this disease, Genetic factors may also modify the disease phenotype without being directly involved in the pathogenesis.
引用
收藏
页码：633 / +
页数：12
相关论文
共 50 条
[21]   RISK FACTORS FOR OSTEOPOROSIS IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE IN INDIA [J].
Gaude, G. S. ;
Karanji, J. .
RESPIROLOGY, 2012, 17 :47-47
[22]   Risk factors for depression in patients with chronic obstructive pulmonary disease [J].
Yayan, Josef ;
Rasche, Kurt .
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY, 2023, 315
[23]   Risk Factors for Venous Thromboembolism in Chronic Obstructive Pulmonary Disease [J].
Kim, Victor ;
Goel, Nishant ;
Gangar, Jinal ;
Zhao, Huaqing ;
Ciccolella, David E. ;
Silverman, Edwin K. ;
Crapo, James D. ;
Criner, Gerard J. .
CHRONIC OBSTRUCTIVE PULMONARY DISEASES-JOURNAL OF THE COPD FOUNDATION, 2014, 1 (02) :239-249
[24]   Risk factors for mortality in patients with chronic obstructive pulmonary disease [J].
Montserrat-Capdevila, Josep ;
Godoy, Pere ;
Ramon Marsal, Josep ;
Barbe-Illa, Ferran .
ATENCION PRIMARIA, 2015, 47 (08) :498-504
[25]   Risk factors for pulmonary embolism in acute exacerbation of chronic obstructive pulmonary disease [J].
李有霞 .
ChinaMedicalAbstracts(InternalMedicine), 2016, 33 (03) :154-155
[26]   PREVALENCE AND RISK FACTORS OF PULMONARY EMBOLISM IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE EXACERBATIONS [J].
Doi Quang Nguyen ;
Thai Hong Hoang ;
Hanh Thi Chu ;
Chau Quy Ngo .
RESPIROLOGY, 2019, 24 :238-239
[27]   A Between Ethnicities Comparison of Chronic Obstructive Pulmonary Disease Genetic Risk [J].
Gim, Jungsoo ;
An, Jaehoon ;
Sung, Joohon ;
Silverman, Edwin K. ;
Cho, Michael H. ;
Won, Sungho .
FRONTIERS IN GENETICS, 2020, 11
[28]   Toward the Identification of a Genetic Risk Signature for Pulmonary Aspergillosis in Chronic Obstructive Pulmonary Disease [J].
Cunha, Cristina ;
Carvalho, Agostinho .
CLINICAL INFECTIOUS DISEASES, 2018, 66 (07) :1153-1154
[29]   Secondary polycythemia in chronic obstructive pulmonary disease: prevalence and risk factors [J].
Jingzhou Zhang ;
Dawn L. DeMeo ;
Edwin K. Silverman ;
Barry J. Make ;
R. Chad Wade ;
J. Michael Wells ;
Michael H. Cho ;
Brian D. Hobbs .
BMC Pulmonary Medicine, 21
[30]   RISK-FACTORS IN CHRONIC OBSTRUCTIVE PULMONARY-DISEASE (COPD) [J].
COHEN, BH ;
BALL, WC ;
BRASHEARS, S ;
DIAMOND, EL ;
KREISS, P ;
LEVY, DA ;
MENKES, HA ;
PERMUTT, S ;
TOCKMAN, MS .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 1977, 105 (03) :223-231
12345