Advances in the management of alveolar soft part sarcoma

被引：19

作者：

Coyne, Geraldine O'Sullivan ^{[1
]}

Naqash, Abdul Rafeh ^{[1
]}

Sankaran, Hari ^{[2
]}

Chen, Alice P. ^{[1
]}

机构：

[1] NCI, Early Clin Trials Dev Program, Div Canc Treatment & Diag, NIH, 31 Ctr Dr,Room 3A44, Bethesda, MD 20892 USA

[2] NCI, Biometr Res Program, Pediat Oncol Branch, NIH, Bethesda, MD 20892 USA

来源：

CURRENT PROBLEMS IN CANCER | 2021年 / 45卷 / 04期

基金：

美国国家卫生研究院;

关键词：

ASPS; ASPL-TFE3 chimeric fusion protein; Tyrosine kinase inhibitors; Immunotherapy; Immune checkpoint inhibition; SPONTANEOUS REGRESSION; TRANSCRIPTION FACTOR; PRECLINICAL ACTIVITY; SELINEXOR; INHIBITOR; TFE3; EXPRESSION; SUNITINIB; GENE; ADOLESCENTS;

D O I：

10.1016/j.currproblcancer.2021.100775

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Alveolar Soft Part Sarcoma is one of the less commonly diagnosed soft tissue sarcoma subtypes, an infrequent subtype within the already rare category of human malignancy of sarcoma. In this article we will summarize the histopathological features, natural history and distinct molecular and biological features that have become increasingly appreciated with newer technologies and precision oncology. We will discuss the contemporary management of this disease as well as emerging treatment options. (c) 2021 Published by Elsevier Inc.

引用

页数：14

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