Multi-center randomized open label phase II trial on three rituximab dosing schemes in immune thrombocytopenia patients

被引：20

作者：

Zwaginga, Jaap J. ^{[1
,2
]}

van der Holt, Bronno ^{[3
]}

te Boekhorst, Peter A. ^{[5
]}

Biemond, Bart J. ^{[4
]}

Levin, Mark-David ^{[6
]}

van der Griend, Rene ^{[9
]}

Brand, Anneke ^{[1
,2
]}

Zweegman, Sonja ^{[8
]}

Pruijt, Hans F. M. ^{[10
]}

Novotny, Vera M. J. ^{[13
]}

Vreugdenhil, Art ^{[7
]}

de Groot, Marco R. ^{[14
]}

de Weerdt, Okke ^{[11
,21
]}

van Pampus, Elisabeth C. M. ^{[12
]}

van Maanen-Lamme, Tanja M. ^{[15
]}

Wittebol, Shulamiet ^{[16
]}

Schipperus, Martin R. ^{[17
]}

Silbermann, Matthijs H. ^{[18
]}

Huijgens, Peter C. ^{[8
]}

Luten, Marleen ^{[3
]}

Hollestein, Rene ^{[3
]}

Brakenhoff, Jan A. C. ^{[19
]}

Schrama, Jolanda G. ^{[20
]}

Valster, Fransje A. A. ^{[21
]}

Velders, Gerjo A. ^{[22
]}

Koene, Harry R. ^{[11
,21
]}

机构：

[1] Leiden Univ, Med Ctr, Dept Immunohematol & Blood Transfus, NL-2300 RA Leiden, Netherlands

[2] Leiden Univ, Med Ctr, Sanquin, Jon J van Rood Ctr Clin Transfus Res, NL-2300 RA Leiden, Netherlands

[3] Erasmus MC, Inst Canc, Clin Trial Ctr, HOVON Data Ctr, Rotterdam, Netherlands

[4] Acad Med Ctr Amsterdam, Dept Hematol, Amsterdam, Netherlands

[5] Erasmus MC, Dept Hematol, Rotterdam, Netherlands

[6] Albert Schweitzer Hosp, Dept Internal Med, Dordrecht, Netherlands

[7] Maxima Med Ctr, Dept Internal Med, Veldhoven, Netherlands

[8] Vrije Univ Amsterdam, Med Ctr, Dept Hematol, Amsterdam, Netherlands

[9] Diakonessen Hosp, Dept Internal Med, Utrecht, Netherlands

[10] Jeroen Bosch Hosp, Dept Internal Med, Den Bosch, Netherlands

[11] St Antonius Hosp, Dept Internal Med, Nieuwegein, Netherlands

[12] Radboud Univ Nijmegen, Med Ctr, Dept Lab Med, NL-6525 ED Nijmegen, Netherlands

[13] Radboud Univ Nijmegen, Med Ctr, Dept Hematol, NL-6525 ED Nijmegen, Netherlands

[14] Med Spectrum Twente, Dept Internal Med, Enschede, Netherlands

[15] Westfriesgasthuis, Dept Internal Med, Hoorn, Netherlands

[16] Meander Hosp, Dept Internal Med, Amersfoort, Netherlands

[17] HagaZiekenhuis, Dept Internal Med, The Hague, Netherlands

[18] Tergooiziekenhuizen, Dept Internal Med, Blaricum, Netherlands

[19] Waterland Hosp, Purmerend, Netherlands

[20] Spaarne Hosp, Dept Internal Med, Hoofddorp, Netherlands

[21] Lievensberg Hosp, Dept Internal Med, Bergen Op Zoom, Netherlands

[22] Gelderse Vallei Hosp, Dept Internal Med, Ede, Netherlands

来源：

HAEMATOLOGICA | 2015年 / 100卷 / 03期

关键词：

immune thrombocytopenia; rituximab; splenectomy delaying; early response; open label phase II; ADULT PATIENTS; PURPURA; SPLENECTOMY; THERAPY; EFFICACY; SAFETY; CHILDREN;

D O I：

10.3324/haematol.2014.110213

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：E90 / E92

页数：3

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