COPII Vesicles Get Supersized by Ubiquitin

被引：3

作者：

Malhotra, Vivek ^{[1
,2
,3
]}

机构：

[1] Ctr Genom Regulat CRG, Dept Cell & Dev Biol, Barcelona 08002, Spain

[2] Univ Pompeu Fabra, Barcelona 08002, Spain

[3] Inst Catalana Recerca & Estudis Avancats, Barcelona 08010, Spain

来源：

CELL | 2012年 / 149卷 / 01期

关键词：

RETICULUM EXIT SITES; COLLAGEN SECRETION; TANGO1;

D O I：

10.1016/j.cell.2012.03.006

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Some proteins are too big to fit into conventional COPII-coated vesicles, which raises the question of how large cargo, such as procollagen fibrils, are exported from the endoplasmic reticulum. Jin et al. (2012) in Nature now report that the creation of oversized vesicles is facilitated by the ubiquitination of the COPII component Sec31p.

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收藏

页码：20 / 21

页数：3

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