Molecular characterization of Enterococcus faecalis N06-0364 with low-level vancomycin resistance harboring a novel D-Ala-D-Ser gene cluster, vanL

被引：96

作者：

Boyd, David A. ^{[1
]}

Willey, Barbara M. ^{[2
,3
]}

Fawcett, Darlene ^{[4
]}

Gillani, Nazira ^{[4
]}

Mulvey, Michael R. ^{[1
]}

机构：

[1] Publ Hlth Agcy Canada, Nosocomial Infect, Natl Microbiol Lab, Winnipeg, MB R3E 3R2, Canada

[2] Univ Hlth Network, Toronto, ON, Canada

[3] Mt Sinai Hosp, Toronto, ON M5G 1X5, Canada

[4] Rouge Valley Hlth Ctr Centenary Site, Scarborough, ON, Canada

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2008年 / 52卷 / 07期

关键词：

D O I：

10.1128/AAC.01516-07

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Enterococcus faecalis N06-0364, exhibiting a vancomycin MIC of 8 mu g/ml, was found to harbor a novel D-Ala-D-Ser gene cluster, designated vanL. The vanL gene cluster was similar in organization to the vanC operon, but the VanT serine racemase was encoded by two separate genes, vanTm(L) (membrane binding) and vanTr(L) (racemase).

引用

页码：2667 / 2672

页数：6

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