Impact of lung volume reduction surgery versus rehabilitation on quality of life

被引:15
作者
Mineo, TC
Ambrogi, V
Pompeo, E
Elia, S
Mineo, D
Bollero, P
Nofroni, I
机构
[1] Univ Roma Tor Vergata, Policlin Tor Vergata, I-00133 Rome, Italy
[2] Univ Roma Tor Vergata, Div Thorac Surg, I-00133 Rome, Italy
[3] Univ Roma Tor Vergata, Div Internal Med, I-00133 Rome, Italy
关键词
emphysema; lung function; lung volume reduction surgery; quality of life;
D O I
10.1183/09031936.03.00025203
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
This study aims at evaluating the effects of lung volume reduction versus respiratory rehabilitation on quality of life, assessed by three different questionnaires. Sixty emphysematous patients were randomised by computer to receive either surgery (n=30) or rehabilitation (n=30). Life quality was evaluated by the Nottingham Health Profile, the Short Form (SF)-36 item and the St George's questionnaires. As reported previously, dyspnoea index, forced expiratory volume in one second, residual volume, 6-min walk test and arterial oxygen tension improved after surgery more than after rehabilitation. Quality of life was significantly improved after surgery as follows Nottingham Health Profile physical mobility; SF-36 physical and social functioning, mental and general health, emotional role; St George's general, activity. At multivariate analysis 6- and 12-month changes after surgery of Short Form-36 physical functioning, general health, and St George's activity domains were significantly correlated with forced expiratory volume in one second, while Short Form-36 social functioning and Nottingham Health Profile isolation correlated with residual volume. Functional and especially symptomatic improvements persisted: dyspnoea index, residual volume, and Short Form-36 and St Georges's physical scores were still significant at 4 yrs. Surgery produces greater and longer effects than rehabilitation on quality of life by improving both physical and psychosocial domains. Symptomatic improvements persisted at 4 yrs.
引用
收藏
页码:275 / 280
页数:6
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