A clean, palladium-catalyzed oxidative esterification of aldehydes using benzyl chloride

被引：15

作者：

Heropoulos, Georgios A. ^{[1
]}

Villalonga-Barber, Carolina ^{[1
]}

机构：

[1] Natl Hellen Res Fdn, Inst Organ & Pharmaceut Chem, Athens 11635, Greece

来源：

TETRAHEDRON LETTERS | 2011年 / 52卷 / 41期

关键词：

Aldehydes; Benzyl chloride; Oxidation; Esterification; Palladium; AROMATIC ESTERIFICATION; ARYL HALIDES; ALCOHOLS; ACIDS; CONVERSION; ESTERS; MILD;

D O I：

10.1016/j.tetlet.2011.08.021

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly efficient, mild, simple and clean procedure is presented for the one-pot oxidation of aromatic and aliphatic aldehydes to their corresponding ethyl esters using benzyl chloride as the oxidant under palladium-catalyzed conditions. The reaction is complete in just 30 min under microwave irradiation and inert conditions are not required to obtain good to excellent yields (65-93%) of isolated products. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：5319 / 5322

页数：4

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