Heat shock proteins are no DAMPs, rather 'DAMPERs'

被引:46
作者
Broere, Femke [1 ]
van der Zee, Ruurd [1 ]
van Eden, Willem [1 ]
机构
[1] Univ Utrecht, Fac Vet Med, Dept Infect Dis & Immunol, NL-3584 CL Utrecht, Netherlands
关键词
T-CELL REGULATION; HEAT-SHOCK-PROTEIN-70; HSP70; DENDRITIC CELLS; GP96; INFLAMMATION; EXPRESSION; SURVIVAL; HOST;
D O I
10.1038/nri2873-c1
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:565 / 565
页数:1
相关论文
共 24 条
[1]   Calcium signaling in dendritic cells by human or mycobacterial Hsp70 is caused by contamination and is not required for Hsp70-mediated enhancement of cross-presentation [J].
Bendz, Henriette ;
Marincek, Boris-Christian ;
Momburg, Frank ;
Ellwart, Joachim W. ;
Issels, Rolf D. ;
Nelson, Peter J. ;
Noessner, Elfriede .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 283 (39) :26477-26483
[2]   Prolonged Survival of Allografts Induced by Mycobacterial Hsp70 Is Dependent on CD4+CD25+Regulatory T Cells [J].
Borges, Thiago J. ;
Porto, Barbara N. ;
Teixeira, Cesar A. ;
Rodrigues, Marcelle ;
Machado, Felipe D. ;
Ornaghi, Ana Paula ;
de Souza, Ana Paula D. ;
Maito, Fabio ;
Pavanelli, Wander R. ;
Silva, Joao S. ;
Bonorino, Cristina .
PLOS ONE, 2010, 5 (12)
[3]   Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells [J].
Chalmin, Fanny ;
Ladoire, Sylvain ;
Mignot, Gregoire ;
Vincent, Julie ;
Bruchard, Melanie ;
Remy-Martin, Jean-Paul ;
Boireau, Wilfrid ;
Rouleau, Alain ;
Simon, Benoit ;
Lanneau, David ;
De Thonel, Aurelie ;
Multhoff, Gabriele ;
Hamman, Arlette ;
Martin, Francois ;
Chauffert, Bruno ;
Solary, Eric ;
Zitvogel, Laurence ;
Garrido, Carmen ;
Ryffel, Bernhard ;
Borg, Christophe ;
Apetoh, Lionel ;
Rebe, Cedric ;
Ghiringhelli, Francois .
JOURNAL OF CLINICAL INVESTIGATION, 2010, 120 (02) :457-471
[4]   Identification of a key pathway required for the sterile inflammatory response triggered by dying cells [J].
Chen, Chun-Jen ;
Kono, Hajime ;
Golenbock, Douglas ;
Reed, George ;
Akira, Shizuo ;
Rock, Kenneth L. .
NATURE MEDICINE, 2007, 13 (07) :851-856
[5]   Sterile inflammation: sensing and reacting to damage [J].
Chen, Grace Y. ;
Nunez, Gabriel .
NATURE REVIEWS IMMUNOLOGY, 2010, 10 (12) :826-837
[6]   Endotoxin contamination in recombinant human heat shock protein 70 (Hsp70) preparation is responsible for the induction of tumor necrosis factor a release by murine macrophages [J].
Gao, BC ;
Tsan, MF .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (01) :174-179
[7]   Stress wars: the direct role of host and bacterial molecular chaperones in bacterial infection [J].
Henderson, Brian ;
Allan, Elaine ;
CoateS, Anthony R. M. .
INFECTION AND IMMUNITY, 2006, 74 (07) :3693-3706
[8]   Caught with their PAMPs down? The extracellular signalling actions of molecular chaperones are not due to microbial contaminants [J].
Henderson, Brian ;
Calderwood, Stuart K. ;
Coates, Anthony R. M. ;
Cohen, Irun ;
van Eden, Willem ;
Lehner, Thomas ;
Pockley, A. Graham .
CELL STRESS & CHAPERONES, 2010, 15 (02) :123-141
[9]   Regional differences in colonic mucosa-associated microbiota determine the physiological expression of host heat shock proteins [J].
Hu, Shien ;
Wang, Yunwei ;
Lichtenstein, Lev ;
Tao, Yun ;
Musch, Mark W. ;
Jabri, Bana ;
Antonopoulos, Dionysios ;
Claud, Erika C. ;
Chang, Eugene B. .
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2010, 299 (06) :G1266-G1275
[10]   Enteric flora and lymphocyte-derived cytokines determine expression of heat shock proteins in mouse colonic epithelial cells [J].
Kojima, K ;
Musch, MW ;
Ren, HY ;
Boone, DL ;
Hendrickson, BA ;
Ma, A ;
Chang, EB .
GASTROENTEROLOGY, 2003, 124 (05) :1395-1407