Advanced polymer architectures with stimuli-responsive properties starting from inimers

被引：27

作者：

Bernaerts, Katrien V. ^{[1
]}

Fustin, Charles-Andre ^{[2
,3
]}

Bomal-D'Haese, Cecile ^{[2
,3
]}

Gohy, Jean-Francois ^{[2
,3
]}

Martins, Jose C. ^{[1
]}

Du Prez, Filip E. ^{[1
]}

机构：

[1] Univ Ghent, Dept Organ Chem, B-9000 Ghent, Belgium

[2] Catholic Univ Louvain, Unite Chim Mat Inorgan & Organ, B-1348 Louvain, Belgium

[3] Catholic Univ Louvain, Res Ctr Micro & Nanomat & Elect Devices CeRMiN, B-1348 Louvain, Belgium

来源：

MACROMOLECULES | 2008年 / 41卷 / 07期

关键词：

D O I：

10.1021/ma702547g

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Novel, well-defined, temperature- and/or pH-sensitive copolymer architectures were prepared by atom transfer radical (co)polymerization (ATRP) of a temperature-sensitive poly(methyl vinyl ether) (PMVE) macromonomer, obtained via living cationic polymerization of MVE initiated with inimer 3,3-diethoxypropyl acrylate. Temperature-sensitive comb architectures were obtained by ATRP homopolymerization (Me6TREN/ CuBr in toluene) of the PMVE macromonomer. ATRP copolymerization of the PMVE macromonomer with tert-butyl acrylate, a hydrolyzable precursor for pH-sensitive acrylic acid (AA), gives statistical graft copolymers. Palm-tree block copolymers containing a linear PtBA (PAA after hydrolysis) block and a branched block based on PMVE macromonomers were also prepared and fully characterized. Using turbidimetry, dynamic light scattering, FT-IR, and NMR, the temperature and/or pH responsiveness of those (co)polymer architectures are compared with the properties of previously synthesized linear block copolymers containing PMVE and PtBA or PAA.

引用

页码：2593 / 2606

页数：14

共 76 条

[1]

ADLER M, 2004, E-POLYMERS, V55, P1

[2] Dual/heterofunctional initiators for the combination of mechanistically distinct polymerization techniques [J].

Bernaerts, Katrien V. ;

Du Prez, Filip E. .

PROGRESS IN POLYMER SCIENCE, 2006, 31 (08) :671-722

[3] pH-Responsive diblock copolymers prepared by the dual initiator strategy [J].

Bernaerts, Katrien V. ;

Willet, Nicolas ;

Van Camp, Wim ;

Jerome, Robert ;

Du Prez, Filip E. .

MACROMOLECULES, 2006, 39 (11) :3760-3769

[4] Design of novel poly(methyl vinyl ether) containing AB and ABC block copolymers by the dual initiator strategy [J].

Bernaerts, KV ;

Du Prez, FE .

POLYMER, 2005, 46 (19) :8469-8482

[5] Synthesis of poly(tetrahydrofuran)-b-polystyrene block copolymers from dual initiators for cationic ring-opening polymerization and atom transfer radical polymerization [J].

Bernaerts, KV ;

Schacht, EH ;

Goethals, EJ ;

Du Prez, FE .

JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2003, 41 (21) :3206-3217

[6]

BUATHONG S, 2004, PMSE PREPR, V91, P328

[7] Thermo-responsive polymer nanoparticles with a core-shell micelle structure as site-specific drug carriers [J].

Cammas, S ;

Suzuki, K ;

Sone, C ;

Sakurai, Y ;

Kataoka, K ;

Okano, T .

JOURNAL OF CONTROLLED RELEASE, 1997, 48 (2-3) :157-164

[8] Effect of solvent on the activation rate parameters for polystyrene and poly(butyl acrylate) macroinitiators in atom transfer radical polymerization [J].

Chambard, G ;

Klumperman, B ;

German, AL .

MACROMOLECULES, 2000, 33 (12) :4417-4421

[9] Effect of molecular architecture of hydrophobically modified poly(N-isopropylacrylamide) on the formation of thermoresponsive core-shell micellar drug carriers [J].

Chung, JE ;

Yokoyama, M ;

Aoyagi, T ;

Sakurai, Y ;

Okano, T .

JOURNAL OF CONTROLLED RELEASE, 1998, 53 (1-3) :119-130

[10] Reversibly thermo-responsive alkyl-terminated poly(N-isopropylacrylamide) core-shell micellar structures [J].

Chung, JE ;

Yokoyama, M ;

Suzuki, K ;

Aoyagi, T ;

Sakurai, Y ;

Okano, T .

COLLOIDS AND SURFACES B-BIOINTERFACES, 1997, 9 (1-2) :37-48

← 1 2 3 4 5 6 7 8 →