An Efficient Synthesis of Pyrrolo[1,2-a]quinazolin-5(1H)-one Derivatives with the Aid of Low-Valent Titanium Reagent

被引：14

作者：

Zhao, Xuan ^{[1
]}

Shi, Da-Qing ^{[1
]}

机构：

[1] Soochow Univ, Coll Chem Chem Engn & Mat Sci, Key Lab Organ Synth Jiangsu Prov, Suzhou 215123, Peoples R China

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2011年 / 48卷 / 03期

关键词：

ONE-POT SYNTHESIS; QUINAZOLINONE; CONVERSION; UREAS; ACIDS;

D O I：

10.1002/jhet.637

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A short and facile synthesis of 2,3,3a, 4-tetrahydropyrrolo[1,2-a] quinazolin-5(1H)-ones and 2,3,3a, 4-tetrahydropyrrolo[1,2-a]quinazoline-1,5-diones in good yields via the novel reductive cyclization of 2-nitrobenzamides with haloketones or 4-oxopentanoic acid promoted by low-valent titanium reagent is described.

引用

页码：634 / 638

页数：5

共 25 条

[1] REACTION OF SOME KETO ACIDS WITH ANTHRANILIC ACID ANTHRANILAMIDES ORTHANILAMIDES AND SALICYLAMIDE [J].