Tomographic Structural Changes of Retinal Layers after Internal Limiting Membrane Peeling for Macular Hole Surgery

被引:20
作者
Faria, Mun Yueh [1 ,2 ]
Ferreira, Nuno P. [1 ,2 ]
Cristovao, Diana M. [3 ]
Mano, Sofia [1 ,2 ]
Sousa, David Cordeiro [1 ,2 ]
Monteiro-Grillo, Manuel [1 ,2 ]
机构
[1] Univ Lisbon, Fac Med, Vis Sci Study Ctr, CECV, Lisbon, Portugal
[2] Hosp Santa Maria, Dept Ophthalmol, Lisbon, Portugal
[3] Inst Oftalmol Dr Gama Pinto, Lisbon, Portugal
关键词
Macular hole; Internal limiting membrane peeling; Optical coherence tomography; Macular structural changes; FOVEAL MICROSTRUCTURE; THICKNESS; IMAGES;
D O I
10.1159/000480243
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: To highlight tomographic structural changes of retinal layers after internal limiting membrane (ILM) peeling in macular hole surgery. Methods: Nonrandomized prospective, interventional study in 38 eyes (34 patients) subjected to pars plana vitrectomy and ILM peeling for idiopathic macular hole. Retinal layers were assessed in nasal and temporal regions before and 6 months after surgery using spectral domain optical coherence tomography. Results: Total retinal thickness increased in the nasal region and decreased in the temporal region. The retinal nerve fiber layer (RNFL), ganglion cell layer (GCL), and inner plexiform layer (IPL) showed thinning on both nasal and temporal sides of the fovea. The thickness of the outer plexiform layer (OPL) increased. The outer nuclear layer (ONL) and outer retinal layers (ORL) increased in thickness after surgery in both nasal and temporal regions. Conclusion: ILM peeling is associated with important alterations in the inner retinal layer architecture, with thinning of the RNFL-GCL-IPL complex and thickening of OPL, ONL, and ORL. These structural alterations can help explain functional outcome and could give indications regarding the extent of ILM peeling, even though peeling seems important for higher rate of hole closure. (C) 2017 S. Karger AG, Basel
引用
收藏
页码:24 / 29
页数:6
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