WT1 - more than a transcription factor?

被引：53

作者：

Englert, C ^{[1
]}

机构：

[1] Forschungszentrum Karlsruhe, Inst Genet, D-76021 Karlsruhe, Germany

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1998年 / 23卷 / 10期

关键词：

D O I：

10.1016/S0968-0004(98)01277-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Wilms tumor-suppressor gene WT1 was originally identified through its involvement in the development of a pediatric kidney tumor. Recent genetic data show that mutations in the WT1 gene cause a variety of other diseases, and new biochemical evidence suggests that the WT1 protein is not only a transcription factor but might also act at the post-transcriptional level.

引用

页码：389 / 393

页数：5

共 53 条

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