ECO-FRIENDLY ONE-POT SYNTHESIS OF 2,4-DISUBSTITUTED THIAZOLES BY GRINDING UNDER CATALYST-AND SOLVENT-FREE CONDITIONS

被引：16

作者：

Ding, Quansehng ^{[1
]}

Zhu, Dongjian ^{[1
]}

Jin, Huile ^{[1
]}

Chen, Jiuxi ^{[1
]}

Ding, Jinchang ^{[1
]}

Wu, Huayue ^{[1
]}

机构：

[1] Wenzhou Univ, Coll Chem & Mat Engn, Wenzhou 325027, Peoples R China

来源：

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2011年 / 186卷 / 02期

关键词：

Catalyst-free; grinding; one-pot; solvent-free; thiazoles; EFFICIENT SYNTHESIS; 2-AMINOTHIAZOLES; AMINOTHIAZOLES; DERIVATIVES; DISULFIDES; CHLORIDE;

D O I：

10.1080/10426507.2010.492366

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

An efficient and facile synthesis of 2,4-disubstituted thiazoles is achieved by a one-pot reaction of aldehydes and alpha-bromoketones with thiosemicarbazide by grinding under catalyst-and solvent-free conditions. This method has notable advantages in terms of simple workup, neat conditions, high yield, reasonably rapid reaction rate, and environmental friendliness.

引用

页码：220 / 224

页数：5

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