Stability analysis of a fractional-order cancer model with chaotic dynamics

被引:32
作者
Naik, Parvaiz Ahmad [1 ]
Zu, Jian [1 ]
Naik, Mehraj-ud-din [2 ]
机构
[1] Xi An Jiao Tong Univ, Sch Math & Stat, Xian 710049, Shaanxi, Peoples R China
[2] Jazan Univ, Dept Chem Engn, Coll Engn, Jazan 45142, Saudi Arabia
基金
中国博士后科学基金; 中国国家自然科学基金;
关键词
Cancer model; Caputo fractional derivative; chaos; stability analysis; TRANSMISSION; EPIDEMIC;
D O I
10.1142/S1793524521500467
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
In this paper, we develop a three-dimensional fractional-order cancer model. The proposed model involves the interaction among tumor cells, healthy tissue cells and activated effector cells. The detailed analysis of the equilibrium points is studied. Also, the existence and uniqueness of the solution are investigated. The fractional derivative is considered in the Caputo sense. Numerical simulations are performed to illustrate the effectiveness of the obtained theoretical results. The outcome of the study reveals that the order of the fractional derivative has a significant effect on the dynamic process. Further, the calculated Lyapunov exponents give the existence of chaotic behavior of the proposed model. Also, it is observed from the obtained results that decrease in fractional-order rho increases the chaotic behavior of the model.
引用
收藏
页数:23
相关论文
共 44 条
[1]   Analysis of a fractional SEIR model with treatment [J].
Almeida, Ricardo .
APPLIED MATHEMATICS LETTERS, 2018, 84 :56-62
[2]   A Mathematical Model to Elucidate Brain Tumor Abrogation by Immunotherapy with T11 Target Structure [J].
Banerjee, Sandip ;
Khajanchi, Subhas ;
Chaudhuri, Swapna .
PLOS ONE, 2015, 10 (05)
[3]  
Basir FA., 2015, Control Cybern, V44, P443
[4]   Periodic and chaotic oscillations in a tumor and immune system interaction model with three delays [J].
Bi, Ping ;
Ruan, Shigui ;
Zhang, Xinan .
CHAOS, 2014, 24 (02)
[5]   Fractional-Order Model of the Disease Psoriasis: A Control Based Mathematical Approach [J].
Cao Xianbing ;
Datta, Abhirup ;
Al Basir, Fahad ;
Roy, Priti Kumar .
JOURNAL OF SYSTEMS SCIENCE & COMPLEXITY, 2016, 29 (06) :1565-1584
[6]   TOPOLOGICAL COMPLEXITY AND PREDICTABILITY IN THE DYNAMICS OF A TUMOR GROWTH MODEL WITH SHILNIKOV'S CHAOS [J].
Duarte, Jorge ;
Januario, Cristina ;
Rodrigues, Carla ;
Sardanyes, Josep .
INTERNATIONAL JOURNAL OF BIFURCATION AND CHAOS, 2013, 23 (07)
[7]   Cancer immunoediting: from immunosurveillance to tumor escape [J].
Dunn, GP ;
Bruce, AT ;
Ikeda, H ;
Old, LJ ;
Schreiber, RD .
NATURE IMMUNOLOGY, 2002, 3 (11) :991-998
[8]   The three Es of cancer immunoediting [J].
Dunn, GP ;
Old, LJ ;
Schreiber, RD .
ANNUAL REVIEW OF IMMUNOLOGY, 2004, 22 :329-360
[9]   CHAOS IN A THREE-DIMENSIONAL CANCER MODEL [J].
Itik, Mehmet ;
Banks, Stephen P. .
INTERNATIONAL JOURNAL OF BIFURCATION AND CHAOS, 2010, 20 (01) :71-79
[10]   Portraying the Effect of Calcium-Binding Proteins on Cytosolic Calcium Concentration Distribution Fractionally in Nerve Cells [J].
Jha, Brajesh Kumar ;
Joshi, Hardik ;
Dave, Devanshi D. .
INTERDISCIPLINARY SCIENCES-COMPUTATIONAL LIFE SCIENCES, 2018, 10 (04) :674-685