IA, database of known ligands of aminoacyl-tRNA synthetases

被引：3
作者：
Torchala, Mieczyslaw
Hoffmann, Marcin
机构：
[1] BioInfoBank Inst, PL-60744 Poznan, Poland
[2] Adam Mickiewicz Univ, Fac Phys, PL-61614 Poznan, Poland
[3] Adam Mickiewicz Univ, Fac Chem, PL-60780 Poznan, Poland
来源：
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN | 2007年 / 21卷 / 09期
关键词：
aminoacyl-tRNA synthetases; aminoacyl-tRNA synthetases inhibitors; molecular docking; virtual high throughput screening; METHIONYL-TRANSFER-RNA; INHIBITORS; POTENT; ANALOGS; SERIES; ADENYLATES; DISCOVERY; DOCKING;
D O I：
10.1007/s10822-007-9135-x
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The IA database contains 240 structures of known inhibitors of aminoacyl- tRNA synthetases. Structures can be downloaded in different file formats (mol, sdf, smile, png). The search engine offers possibility of searching for the ligands with a given functional group. Additionally, one can search for ligands that act on selected synthetases and from particular references. The data include information which synthetase a given ligand inhibits together with the inhibition constant (IC50) if known.
引用
收藏
页码：523 / 525
页数：3
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