Facing the Challenges of Chronic Pruritus: A Report From a Multi-disciplinary Medical Itch Centre in Germany

被引：40

作者：

Staender, Sonja ^{[1
]}

Pogatzki-Zahn, Esther ^{[2
]}

Stumpf, Astrid ^{[3
]}

Fritz, Fleur ^{[4
]}

Pfleiderer, Bettina ^{[5
]}

Ritzkat, Anika ^{[5
]}

Bruland, Philipp ^{[4
]}

Lotts, Tobias ^{[1
]}

Mueller-Tidow, Carsten ^{[6
]}

Heuft, Gereon

Pavenstaedt, Hermann-Joseph ^{[7
]}

Schneider, Gudrun ^{[3
]}

Van Aken, Hugo ^{[2
]}

Heindel, Walter ^{[5
]}

Wiendl, Heinz ^{[8
]}

Dugas, Martin ^{[4
]}

Luger, Thomas A. ^{[1
]}

机构：

[1] Univ Hosp Munster, Competence Ctr Chron Pruritus, Dept Dermatol, DE-48149 Munster, Germany

[2] Univ Hosp Munster, Competence Ctr Chron Pruritus, Dept Anesthesiol Intens Care Med & Pain Therapy, DE-48149 Munster, Germany

[3] Univ Hosp Munster, Competence Ctr Chron Pruritus, Dept Psychosomat & Psychotherapy, DE-48149 Munster, Germany

[4] Univ Hosp Munster, Competence Ctr Chron Pruritus, Inst Med Informat, DE-48149 Munster, Germany

[5] Univ Hosp Munster, Competence Ctr Chron Pruritus, Dept Clin Radiol, DE-48149 Munster, Germany

[6] Univ Hosp Munster, Competence Ctr Chron Pruritus, Dept Med A Hematol & Oncol, DE-48149 Munster, Germany

[7] Univ Hosp Munster, Competence Ctr Chron Pruritus, Dept Med D, Div Gen Internal Med Nephrol & Rheumatol, DE-48149 Munster, Germany

[8] Univ Hosp Munster, Competence Ctr Chron Pruritus, Dept Neurol, DE-48149 Munster, Germany

来源：

ACTA DERMATO-VENEREOLOGICA | 2015年 / 95卷 / 03期

关键词：

Competence Center Chronic Pruritus; itch clinics; prurigo nodularis; brachioradial pruritus; aprepitant; nerve fibre density; substance P; neurodermatology; BRACHIORADIAL PRURITUS; INTERNATIONAL FORUM; NERVE-FIBERS; PAIN; MODULATION; GUIDELINE; NODULARIS; SKIN; ARCHITECTURE; PERCEPTION;

D O I：

10.2340/00015555-1949

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The complex nature and difficult-to-establish aetiology of chronic pruritus (CP) makes it challenging to provide medical care for patients with CP. This challenge can only be met with a multidisciplinary approach. The first multidisciplinary Itch Centre in Germany was established at the University of Miinster in 2002 to meet the needs of this patient population. More than 2,500 outpatients and 400 inpatients are diagnosed and receive treatment each year. To ensure evidence-based medical care, an electronic system for medical documentation and patient-reported outcomes was established. Automated data transfer to a research database enables comprehensive data analysis. Our translational research has characterized peripheral and central itch mechanisms, provided novel clustering of CP patients, and identified novel target-specific therapies (e.g. neurokinin 1 receptor-antagonist). The multidisciplinary approach, combined with basic, clinical and translational research, enables comprehensive medical care of patients as well as implementation of high-quality experimental and clinical studies.

引用

页码：266 / 271

页数：6

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