USE OF AXILLARY ULTRASOUND, ULTRASOUND-FINE NEEDLE ASPIRATION BIOPSY AND MAGNETIC RESONANCE IMAGING IN THE PREOPERATIVE TRIAGE OF BREAST CANCER PATIENTS CONSIDERED FOR SENTINEL NODE BIOPSY

被引:55
作者
Garcia Fernandez, Antonio [1 ]
Fraile, M. [1 ]
Gimenez, N. [1 ]
Rene, A. [1 ]
Torras, M. [1 ]
Canales, L. [1 ]
Torres, J. [1 ]
Barco, I. [1 ]
Gonzalez, S. [1 ]
Veloso, E. [1 ]
Gonzalez, C. [1 ]
Cirera, L. [1 ]
Pessarrodona, A. [1 ]
机构
[1] Univ Barcelona, Dept Pathol, Univ Hosp Mutua Terrassa, Res Fdn Mutua Terrassa, Barcelona 08221, Spain
关键词
Breast neoplasms; Sensitivity and specificity; Sentinel lymph node biopsy; Axillary ultrasound; Magnetic resonance imaging; Fine-needle aspiration; LYMPH-NODES; METASTASES; ULTRASONOGRAPHY; CARCINOMA; DIAGNOSIS; MORBIDITY; ACCURACY; CYTOLOGY; UTILITY; NUMBER;
D O I
10.1016/j.ultrasmedbio.2010.10.011
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
We assessed the diagnostic yield of axillary ultrasound, alone or in combination with fine-needle aspiration axillary biopsy and magnetic resonance imaging in patients with invasive breast carcinoma compared with final axillary histology by sentinel node biopsy or by axillary lymph node dissection. From January 2003 to March 2009, 520 axillary ultrasound examinations and 105 axillary magnetic resonance imaging studies were included. Compared with final axillary histology, ultrasound fine-needle aspiration showed positive predictive value of 87%, negative predictive value of 82%, sensitivity of 53% and specificity of 100%. In cases of negative ultrasound, the rate of positive nodes was 17% (micro-metastases excluded). Ultrasound examination of the axilla, combined with fine-needle aspiration as appropriate must be included in the preoperative work-up of patients considered for sentinel node biopsy to definitively establish such an indication while minimizing the risk of false-negative sentinel node. Axillary magnetic resonance imaging did not improve the preoperative work-up. (E-mail: agarcia@mutuaterrassa.es) (C) 2011 World Federation for Ultrasound in Medicine & Biology.
引用
收藏
页码:16 / 22
页数:7
相关论文
共 27 条
[1]   Axillary Lymph Nodes Suspicious for Breast Cancer Metastasis: Sampling with US-guided 14-Gauge Core-Needle Biopsy-Clinical Experience in 100 Patients [J].
Abe, Hiroyuki ;
Schmidt, Robert A. ;
Kulkarni, Kirti ;
Sennett, Charlene A. ;
Mueller, Jeffrey S. ;
Newstead, Gillian M. .
RADIOLOGY, 2009, 250 (01) :41-49
[2]   Role of sonography in the diagnosis of axillary lymph node metastases in breast cancer:: A systematic review [J].
Alvarez, S ;
Añorbe, E ;
Alcorta, P ;
López, F ;
Alonso, I ;
Cortés, J .
AMERICAN JOURNAL OF ROENTGENOLOGY, 2006, 186 (05) :1342-1348
[3]   Impact of clinicopathological factors on sensitivity of axillary ultrasonography in the detection of axillary nodal metastases in patients with breast cancer [J].
Bedrosian, I ;
Bedi, D ;
Kuerer, HM ;
Fornage, BD ;
Harker, L ;
Ross, MI ;
Ames, FC ;
Krishnamurthy, S ;
Edeiken-Monroe, BS ;
Meric, F ;
Feig, BW ;
Akins, J ;
Singletary, E ;
Mirza, NQ ;
Hunt, KK .
ANNALS OF SURGICAL ONCOLOGY, 2003, 10 (09) :1025-1030
[4]   Ultrasound-guided aspiration biopsy for detection of nonpalpable axillary node metastases in breast cancer patients: New diagnostic method [J].
Bonnema, J ;
vanGeel, AN ;
vanOoijen, B ;
Mali, SPM ;
Tjiam, SL ;
HenzenLogmans, SC ;
Schmitz, PIM ;
Wiggers, T .
WORLD JOURNAL OF SURGERY, 1997, 21 (03) :270-274
[5]   Utility of ultrasound and fine-needle aspiration biopsy of the axilla in the assessment of invasive lobular carcinoma of the breast [J].
Boughey, Judy C. ;
Middleton, Lavinia P. ;
Harker, Lori ;
Garrett, Betsy ;
Fornage, Bruno ;
Hunt, Kelly K. ;
Babiera, Gildy V. ;
Dempsey, Peter ;
Bedrosian, Isabelle .
AMERICAN JOURNAL OF SURGERY, 2007, 194 (04) :450-455
[6]  
Brancato Beniamino, 2004, Radiol Med, V108, P345
[7]   AXILLARY LYMPH-NODE METASTASES IN BREAST-CANCER - PREOPERATIVE DETECTION WITH US [J].
BRUNETON, JN ;
CARAMELLA, E ;
HERY, M ;
AUBANEL, D ;
MANZINO, JJ ;
PICARD, JL .
RADIOLOGY, 1986, 158 (02) :325-326
[8]   Accuracy of fine needle aspiration cytology (FNAC) of axillary lymph nodes as a triage test in breast cancer staging [J].
Ciatto, Stefano ;
Brancato, Beniamino ;
Risso, Gabriella ;
Ambrogetti, Daniela ;
Bulgaresi, Paolo ;
Maddau, Cristina ;
Turco, Patricia ;
Houssami, Nehmat .
BREAST CANCER RESEARCH AND TREATMENT, 2007, 103 (01) :85-91
[9]   Diagnosis of axillary nodal metastases by ultrasound-guided core biopsy in primary operable breast cancer [J].
Damera, A ;
Evans, AJ ;
Cornford, EJ ;
Wilson, ARM ;
Burrell, HC ;
James, JJ ;
Pinder, SE ;
Ellis, IO ;
Lee, AHS ;
Macmillan, RD .
BRITISH JOURNAL OF CANCER, 2003, 89 (07) :1310-1313
[10]  
DEFREITAS R, 1991, EUR J SURG ONCOL, V17, P240