Laboratory testing for antiphospholipid syndrome

被引：19

作者：

Pengo, V. ^{[1
,2
]}

Banzato, A. ^{[1
,2
]}

Bison, E. ^{[1
,2
]}

Denas, G. ^{[1
,2
]}

Zoppellaro, G. ^{[1
,2
]}

Bracco, A. ^{[1
,2
]}

Jose, S. Padayattil ^{[1
,2
]}

Hoxha, A. ^{[3
]}

Ruffatti, A. ^{[3
]}

机构：

[1] Univ Padua, Clin Cardiol, Dept Cardiac Thorac & Vasc Sci, Padua, Italy

[2] Univ Padua, Div Rheumatol, Padua, Italy

[3] Univ Padua, Dept Med, Padua, Italy

来源：

INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY | 2016年 / 38卷

关键词：

Phospholipid; syndrome; testing; laboratory; 1ST THROMBOEMBOLIC EVENT; LUPUS ANTICOAGULANT; ANTIBODY PROFILE; CLINICAL-COURSE; ANTICARDIOLIPIN; PERFORMANCE; POSITIVITY; DIAGNOSIS; CARRIERS; UPDATE;

D O I：

10.1111/ijlh.12507

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This is a practical report on laboratory tests for the diagnosis of antiphospholipid syndrome (APS). After a general definition of APS, this study deals with appropriateness and timing in requesting the determination of antiphospholipid (aPL) antibodies. Lupus anticoagulant (LAC), anticardiolipin (aCL), and anti 2-glycoprotein I (aGPI) are the mandatory tests to be performed, while other tests are not yet validated for clinical use. Interpretation of results is an important discussed issue that implies a close liaison between clinical pathologists and clinicians. Finally, a personal definition of APS according to aPL antibody profile closes the manuscript.

引用

页码：27 / 31

页数：5

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