Laboratory testing for antiphospholipid syndrome

被引：18
作者：
Pengo, V. [1 ,2 ]
Banzato, A. [1 ,2 ]
Bison, E. [1 ,2 ]
Denas, G. [1 ,2 ]
Zoppellaro, G. [1 ,2 ]
Bracco, A. [1 ,2 ]
Jose, S. Padayattil [1 ,2 ]
Hoxha, A. [3 ]
Ruffatti, A. [3 ]
机构：
[1] Univ Padua, Clin Cardiol, Dept Cardiac Thorac & Vasc Sci, Padua, Italy
[2] Univ Padua, Div Rheumatol, Padua, Italy
[3] Univ Padua, Dept Med, Padua, Italy
来源：
INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY | 2016年 / 38卷
关键词：
Phospholipid; syndrome; testing; laboratory; 1ST THROMBOEMBOLIC EVENT; LUPUS ANTICOAGULANT; ANTIBODY PROFILE; CLINICAL-COURSE; ANTICARDIOLIPIN; PERFORMANCE; POSITIVITY; DIAGNOSIS; CARRIERS; UPDATE;
D O I：
10.1111/ijlh.12507
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
This is a practical report on laboratory tests for the diagnosis of antiphospholipid syndrome (APS). After a general definition of APS, this study deals with appropriateness and timing in requesting the determination of antiphospholipid (aPL) antibodies. Lupus anticoagulant (LAC), anticardiolipin (aCL), and anti 2-glycoprotein I (aGPI) are the mandatory tests to be performed, while other tests are not yet validated for clinical use. Interpretation of results is an important discussed issue that implies a close liaison between clinical pathologists and clinicians. Finally, a personal definition of APS according to aPL antibody profile closes the manuscript.
引用
收藏
页码：27 / 31
页数：5
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