The tailoring of the particle and powder properties that are produced within spray processes is influenced by various unsteady transport processes in the dispersed multiphase spray flow in a confined spray chamber. In this context differently scaled spray structures in a confined spray environment have been analyzed experimentally and numerically. The basic setup of the study consists of a twin-fluid atomizer central top-spraying in a confined spray chamber, where the atomizer gas can be heated up to 500 degrees C. Mixing phenomena of momentum, energy and species play an even bigger role for this hot-gas atomization and drying process than in a conventional tall form spray dryer. The experimental investigations have been carried out with Particle-Image-Velocimetry to determine the kinetic data of the gas and the discrete phase. Additionally Large-Eddy-Simulations have been set up to predict the transient behaviour of the process and give more insight into the sensitivity of the droplet-gas interactions.