Opposite enantioselectivities of two phenotypically and genotypically similar strains of Pseudomonas frederiksbergensis in bacterial whole-cell sulfoxidation

被引：10
作者：
Adam, W
Heckel, F
Saha-Möller, CR
Taupp, M
Meyer, JM
Schreier, P
机构：
[1] Univ Wurzburg, Inst Food Chem, D-97074 Wurzburg, Germany
[2] Univ Wurzburg, Inst Organ Chem, D-97074 Wurzburg, Germany
[3] Facundo Univ Puerto Rico, Dept Chem, Rio Piedras, PR USA
[4] Univ Strasbourg 1, Lab Microbiol & Genet, Strasbourg, France
来源：
APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 2005年 / 71卷 / 04期
关键词：
D O I：
10.1128/AEM.71.4.2199-2202.2005
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Soil samples were screened to select microorganisms with the capability to oxidize organic sulfides into the corresponding sulfoxides with differential enantioselectivities. Several bacterial strains that preferentially produced the S-configured sulfoxide enantiomer were isolated. Surprisingly, one bacterial strain, genotypically and phenotypically characterized as Pseudomonas frederiksbergensis, selectively gave the R enantiomer. The finding that two apparently identical organisms displayed opposite enantioselectivities is novel for nongenetically modified organisms.
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页码：2199 / 2202
页数：4
相关论文
共 24 条
[1]  
Adam W, 1999, Adv Biochem Eng Biotechnol, V63, P73
[2]   A highly enantioselective biocatalytic sulfoxidation by the topsoil bacterium Pseudomonas frederiksbergensis [J].
Adam, W ;
Heckel, F ;
Saha-Möller, CR ;
Taupp, M ;
Schreier, P .
TETRAHEDRON-ASYMMETRY, 2004, 15 (06) :983-985
[3]   Biocatalytic synthesis of optically active oxyfunctionalized building blocks with enzymes, chemoenzymes and microorganisms [J].
Adam, W ;
Heckel, F ;
Saha-Möller, CR ;
Schreier, P .
JOURNAL OF ORGANOMETALLIC CHEMISTRY, 2002, 661 (1-2) :17-29
[4]   Titanium-catalyzed, asymmetric sulfoxidation of alkyl aryl sulfides with optically active hydroperoxides [J].
Adam, W ;
Korb, MN ;
Roschmann, KJ ;
Saha-Möller, CR .
JOURNAL OF ORGANIC CHEMISTRY, 1998, 63 (10) :3423-3428
[5]   Asymmetric synthesis with the enzyme Coprinus peroxidase:: Kinetic resolution of chiral hydroperoxides and enantioselective sulfoxidation [J].
Adam, W ;
Mock-Knoblauch, C ;
Saha-Möller, CR .
JOURNAL OF ORGANIC CHEMISTRY, 1999, 64 (13) :4834-4839
[6]   Pseudomonas frederiksbergensis sp nov., isolated from soil at a coal gasification site [J].
Andersen, SM ;
Johnsen, K ;
Sorensen, J ;
Nielsen, P ;
Jacobsen, CS .
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, 2000, 50 :1957-1964
[7]  
Atlas R. M., 1993, HDB MICROBIOLOGICAL
[8]  
BOYD RB, 1998, J CHEM SOC P1, V12, P1929
[9]   Enzyme-mediated catalytic asymmetric oxidations [J].
Colonna, S ;
Del Sordo, S ;
Gaggero, N ;
Carrea, G ;
Pasta, P .
HETEROATOM CHEMISTRY, 2002, 13 (05) :467-473
[10]   CHLOROPEROXIDASE AND HYDROGEN-PEROXIDE - AN EFFICIENT SYSTEM FOR ENZYMATIC ENANTIOSELECTIVE SULFOXIDATIONS [J].
COLONNA, S ;
GAGGERO, N ;
CASELLA, L ;
CARREA, G ;
PASTA, P .
TETRAHEDRON-ASYMMETRY, 1992, 3 (01) :95-106
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