Impacts of parathyroidectomy on renal anemia and nutritional status of hemodialysis patients with secondary hyperparathyroidism

被引:6
作者
Chen, Chen [1 ]
Wu, Hua [1 ]
Zhong, Lin [1 ]
Wang, Xin [1 ]
Xing, Zhuang-Jie [2 ]
Gao, Bi-Hu [1 ]
机构
[1] Dalian Univ, Affiliated Zhongshan Hosp, Dept Nephrol, Dalian 116000, Peoples R China
[2] Dalian Univ, Affiliated Zhongshan Hosp, Dept Vasc Surger, Dalian 116000, Peoples R China
来源
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE | 2015年 / 8卷 / 06期
关键词
Parathyroidectomy; secondary hyperparathyroidism; renal anemia; nutrition; HORMONE; DISEASE; ERYTHROPOIETIN; PARAMETERS; FAILURE;
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The aim of this study was to investigate the impacts of parathyroidectomy (PTX) towards the renal anemia and nutritional status of hemodialysis patients with secondary hyperparathyroidism (SHPT). 32 patients, enrolled into the blood purification center of our hospital for the hemodialysis treatment, were collected and divided into the PTX group and the non-PTX group, with 16 patients in each group. The changes of relevant indicators such as immunoreactive parathyroid hormone (iPTH), anemia and nutrition were observed before, 1-, 3-, 6-month after the treatment. The contents of iPTH, Ca, P and Ca x P of the PTX group decreased rapidly 1 month after the surgery; while Hb and Hct increased significantly from the 1st postoperative month; the dosage of EPO was significantly reduced 3-month after the surgery; the content of Alb gradually increased from the 3rd postoperative month; the content of TG decreased significantly from the 6th postoperative month; while the contents of BMI and TSF increased significantly from the 6th postoperative month, which exhibited the statistically significant differences when compared with the preoperative and the non-PTX group (P < 0.05). PTX could quickly reduce the iPTH level and significantly improve the renal anemia and nutritional status; SHPT was the important factor that would affect the renal anemia and malnutrition; PTX could reduce the amount of EPO, and reduce the economic burden of patients.
引用
收藏
页码:9830 / 9838
页数:9
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