Should Postmastectomy Radiotherapy to the Chest Wall and Regional Lymph Nodes Be Standard for Patients with 1-3 Positive Lymph Nodes?

被引:6
作者
Offersen, Birgitte V. [1 ]
Brodersen, Hans-Juergen [2 ]
Nielsen, Mette M. [3 ]
Overgaard, Jens [4 ]
Overgaard, Marie [1 ]
机构
[1] Aarhus Univ Hosp, Dept Oncol, DK-8000 Aarhus C, Denmark
[2] Malteser Krankenhaus St Franziskus Hosp, Klin Strahlentherapie, Flensburg, Germany
[3] Odense Univ Hosp, Dept Oncol, Odense, Denmark
[4] Aarhus Univ Hosp, Dept Expt Clin Oncol, DK-8000 Aarhus C, Denmark
关键词
Postmastectomy radiotherapy; Breast cancer; Positive lymph nodes; Randomized clinical trial; RISK BREAST-CANCER; INTERNATIONAL EXPERT CONSENSUS; CLINICAL-PRACTICE GUIDELINES; PRIMARY THERAPY; POSTOPERATIVE RADIOTHERAPY; PREMENOPAUSAL WOMEN; SYSTEMIC TREATMENT; SUBGROUP ANALYSIS; HEART-DISEASE; HIGHLIGHTS;
D O I
10.1159/000333250
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The indication for adjuvant postmastectomy radiotherapy (PMRT) in breast cancer patients with small tumors and 1-3 macrometastases in the axilla remains a controversial issue, despite the recommendation that PMRT should be applied in these patients in the most recent overview by the Early Breast Cancer Trialists' Collaborative Group. In this report, we discuss the available data on the benefit from PMRT in patients diagnosed with N1 breast cancer. Based on this, we recommend adjuvant PMRT to the chest wall and regional lymph nodes in patients diagnosed with early node-positive breast cancer.
引用
收藏
页码:347 / 351
页数:5
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