Adjuvant Temozolomide Chemotherapy for Treatment of Papillary Tumor of the Pineal Region

被引：18

作者：

Lorenzetti, Martin ^{[1
]}

Motta, Federica ^{[1
]}

Campanella, Rolando ^{[1
]}

Bauer, Dario ^{[2
,3
]}

Assi, Agnese ^{[4
]}

Arienta, Cesare ^{[5
]}

Gaini, Sergio Maria ^{[1
]}

Caroli, Manuela ^{[1
]}

机构：

[1] Osped Maggiore, Ist Ricovero & Cura Carattere Sci, Fdn Policlin, Dept Neurol Sci, Milan, Italy

[2] Univ Milan, AO San Paolo, Div Patholgy, Dept Med Surg & Dent, Milan, Italy

[3] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Milan, Italy

[4] Osped Civile Legnano, Legnano, Italy

[5] Osped San Matteo, Pavia, Italy

来源：

WORLD NEUROSURGERY | 2011年 / 76卷 / 1-2期

关键词：

Chemotherapy; Papillary pineocytoma; Papillary tumor of the pineal region; Temozolomide; PARENCHYMAL TUMORS; PINEOCYTOMA; FEATURES;

D O I：

10.1016/j.wneu.2010.10.039

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

BACKGROUND: We present a personal case of papillary pineocytoma in a 42-year-old woman. METHODS: The lesion was first treated surgically both for diagnostic aims and for resolution of the mass effect causing hydrocephalus and correlated neurological disturbances. Because the tumor recurred after surgery and radiotherapy, we decided to further treat the patient with chemotherapy, in particular with temozolomide. RESULTS: Currently, almost 9 years after the first treatment, the patient is symptom-free and follow-up magnetic resonance imaging shows no tumor recurrence. CONCLUSION: Although surgery should be considered the first-choice therapy, we think that temozolomide can be a valid option in case of recurrence of these rare tumors.

引用

页码：160 / 163

页数：4

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