Multimodal probe for optical coherence tomography epidetection and micron-scale indentation

被引:4
|
作者
Bartolini, L. [1 ]
Feroldi, F.
Weda, J. J. A.
Slaman, M.
de Boer, J. F.
Iannuzzi, D.
机构
[1] Vrije Univ Amsterdam, Dept Phys & Astron, Boelelaan 1081, NL-1081 HV Amsterdam, Netherlands
基金
欧洲研究理事会;
关键词
Optomechanical; microindentation; optical coherence tomography; indentation; multimodal sensor; epidetection; ELASTOGRAPHY; TISSUE; MECHANICS; HYDROGELS; CARTILAGE; STRAIN; SKIN; OCT;
D O I
10.1142/S179354581742007X
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We present a multimodal ferrule-top sensor designed to perform the integrated epidetection of Optical Coherence Tomography (OCT) depth-proflles and micron-scale indentation by all-optical detection. By scanning a sample under the probe, we can obtain structural cross-section images and identify a region-of-interest in a nonhomogeneous sample. Then, with the same probe and setup, we can immediately target that area with a series of spherical-indentation measurements, in which the applied load is known with a mu N precision, the indentation depth with sub-mu m precision and a maximum contact radius of 100 mu m. Thanks to the visualization of the internal structure of the sample, we can gain a better insight into the observed mechanical behavior. The ability to impart a small, confined load, and perform OCT A-scans at the same time, could lead to an alternative, high transverse resolution, Optical Coherence Elastography (OCE) sensor.
引用
收藏
页数:9
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