Comparative efficacy of three commercial PCV2 vaccines in conventionally reared pigs

被引:30
作者
Lyoo, KwangSoo [1 ]
Joo, HanSoo [1 ]
Caldwell, Brian [2 ]
Kim, HyeunBum [1 ]
Davies, Peter R. [1 ]
Torrison, Jerry [1 ]
机构
[1] Univ Minnesota, Coll Vet Med, Dept Vet Populat Med, St Paul, MN 55108 USA
[2] Choice Connect, Mapleton, MN 56065 USA
关键词
Porcine circovirus type 2; Vaccine; Conventional pigs; Efficacy; PORCINE CIRCOVIRUS TYPE-2; MULTISYSTEMIC WASTING SYNDROME; EXPERIMENTAL-INFECTION; MATERNAL ANTIBODIES; VACCINATION; PMWS; GENOTYPES; SWINE; PROTECTION; DISEASE;
D O I
10.1016/j.tvjl.2010.06.015
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
The aim of this study was to compare the efficacy of three commercial porcine circovirus type 2 (PCV2) vaccines. Twenty 3-week old pigs were injected with one of three different vaccines, A, B, C, or were unvaccinated controls. Pigs in group A were given a second dose at 6 weeks of age according to the manufacturer's protocol. Antibody titers in all pigs declined gradually, but increased sharply by 22 weeks of age. Viremia in the three vaccinated groups at 22 weeks of age was significantly less than in the control group. The average daily gains of pigs in groups A-C. and in controls were 0.81 +/- 0.03, 0.80 +/- 0.05, 0.78 +/- 0.04. and 0.74 +/- 0.05 kg, respectively. It was concluded that PCV2 vaccine reduced viremia and improved weight gain, but differences in weight gain among vaccinated groups were not statistically significant. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码:58 / 62
页数:5
相关论文
共 26 条
[1]   Protection of swine against post-weaning multisystemic wasting syndrome (PMWS) by porcine circovirus type 2 (PCV2) proteins [J].
Blanchard, P ;
Mahé, D ;
Cariolet, R ;
Keranflec'h, A ;
Baudouard, MA ;
Cordioli, P ;
Albina, E ;
Jestin, A .
VACCINE, 2003, 21 (31) :4565-4575
[2]   Detection of two porcine circovirus type 2 genotypic groups in United States swine herds [J].
Cheung, A. K. ;
Lager, K. M. ;
Kohutyuk, O. I. ;
Vincent, A. L. ;
Henry, S. C. ;
Baker, R. B. ;
Rowland, R. R. ;
Dunham, A. G. .
ARCHIVES OF VIROLOGY, 2007, 152 (05) :1035-1044
[3]   Genomic analysis of PCV2 isolates from Danish archives and a current PMWS case-control study supports a shift in genotypes with time [J].
Dupont, K. ;
Nielsen, E. O. ;
Baekbo, P. ;
Larsen, L. E. .
VETERINARY MICROBIOLOGY, 2008, 128 (1-2) :56-64
[4]   The effect of vaccination against porcine circovirus type 2 in pigs suffering from porcine respiratory disease complex [J].
Fachinger, Vicky ;
Bischoff, Ralf ;
Ben Jedidia, Samir ;
Saalmueller, Armin ;
Elbers, Knut .
VACCINE, 2008, 26 (11) :1488-1499
[5]   A chimeric porcine circovirus (PCV) with the immunogenic capsid gene of the pathogenic PCV type 2 (PCV2) cloned into the genomic backbone of the nonpathogenic PCV1 induces protective immunity against PCV2 infection in pigs [J].
Fenaux, M ;
Opriessnig, T ;
Halbur, PG ;
Elvinger, F ;
Meng, XJ .
JOURNAL OF VIROLOGY, 2004, 78 (12) :6297-6303
[6]   Porcine circovirus type 2 (PCV2) vaccination of conventional pigs prevents viremia against PCV2 isolates of different genotypes and geographic origins [J].
Fort, M. ;
Sibila, M. ;
Allepuz, A. ;
Mateu, E. ;
Roerink, F. ;
Segales, J. .
VACCINE, 2008, 26 (08) :1063-1071
[7]   Detection of neutralizing antibodies in postweaning multisystemic wasting syndrome (PMWS)-affected and non-PMWS-affected pigs [J].
Fort, Maria ;
Olvera, Alex ;
Sibila, Marina ;
Segales, Joaquim ;
Mateu, Enric .
VETERINARY MICROBIOLOGY, 2007, 125 (3-4) :244-255
[8]  
Gagnon CA, 2007, CAN VET J, V48, P811
[9]   Nucleotide sequence of porcine circovirus associated with postweaning multisystemic wasting syndrome in pigs [J].
Hamel, AL ;
Lin, LL ;
Nayar, GPS .
JOURNAL OF VIROLOGY, 1998, 72 (06) :5262-5267
[10]   A field evaluation of mortality rate and growth performance in pigs vaccinated against porcine circovirus type 2 [J].
Horlen, Kyle P. ;
Dritz, Steve S. ;
Nietfeld, Jerome C. ;
Henry, Steven C. ;
Hesse, Richard A. ;
Oberst, Richard ;
Hays, Michael ;
Anderson, Joseph ;
Rowland, Raymond R. R. .
JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 2008, 232 (06) :906-912