Self-assembling peptide polyelectrolyte β-sheet complexes form nematic hydrogels

被引：118

作者：

Aggeli, A ^{[1
]}

Bell, M ^{[1
]}

Boden, N ^{[1
]}

Carrick, LM ^{[1
]}

Strong, AE ^{[1
]}

机构：

[1] Univ Leeds, Dept Chem, Ctr Self Organising Mol Syst, Leeds LS2 9JT, W Yorkshire, England

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2003年 / 42卷 / 45期

关键词：

beta-sheets; gels; peptides; phase transitions; self-assembly;

D O I：

10.1002/anie.200352207

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Fibrillar networks built up from polyelectrolyte β-sheet complexes (see picture) are formed by spontaneous self-assembly when solutions of appropriately designed cationic and anionic oligopeptides are mixed. At the macroscopic level the resulting solutions are nematic hydrogels, which are quite robust to variations in pH or peptide concentration.

引用

页码：5603 / 5606

页数：4

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