Novel molecular screening approaches in colorectal cancer

被引:43
作者
Miller, Seth [1 ]
Steele, Scott [1 ]
机构
[1] Madigan Army Med Ctr, Dept Gen Surg, Tacoma, WA 98431 USA
关键词
colorectal cancer (CRC); molecular screening; FECAL-OCCULT-BLOOD; HUMAN COLON-CANCER; CT COLONOGRAPHY; VIRTUAL COLONOSCOPY; OPTICAL COLONOSCOPY; ASYMPTOMATIC ADULTS; IMMUNOCHEMICAL TEST; BOWEL PREPARATION; AMERICAN-COLLEGE; GENE-EXPRESSION;
D O I
10.1002/jso.21704
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Traditional methods for colorectal cancer (CRC) screening have reduced rates of malignancy and death; however, low compliance and morbidities associated with invasive techniques have encouraged efforts for establishing equally effective, less invasive novel screening approaches. We review the current state of novel screening approaches in CRC to include CT colonography, fecal DNA, DNA methylation, micro-RNA, and protein and molecular markers. J. Surg. Oncol. 2012; 105:459467. (c) 2012 Wiley Periodicals, Inc.
引用
收藏
页码:459 / 467
页数:9
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