Decelerated chirality interconversion of an optically inactive 310-helical peptide by metal chelation

被引:14
|
作者
Ousaka, Naoki [1 ]
Tani, Norihiko [2 ]
Sekiya, Ryo [2 ]
Kuroda, Reiko [1 ,2 ]
机构
[1] ERATO SORST Kuroda Chiromorphol Team, Japan Sci & Technol Agcy, Meguro Ku, Tokyo 1530041, Japan
[2] Univ Tokyo, Dept Life Sci, Grad Sch Arts & Sci, Meguro Ku, Tokyo 1538902, Japan
关键词
D O I
10.1039/b803080d
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A dynamically optically inactive 3(10)-helical peptide possessing metal chelating ability between the side-chains at the i and i + 3th residues was synthesized, and its metal complexes were shown to stabilize the peptide structure and the helical sense.
引用
收藏
页码:2894 / 2896
页数:3
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