Time to reconsider our approach to echogenic intracardiac focus and choroid plexus cysts

被引：15

作者：

Bethune, Michael ^{[1
,2
,3
]}

机构：

[1] Melbourne Ultrasound Women, Melbourne, Vic, Australia

[2] Royal Hosp Women, Ultrasound Dept, Melbourne, Vic, Australia

[3] Mercy Hosp Women, Dept Med Imaging, Melbourne, Vic, Australia

来源：

AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY | 2008年 / 48卷 / 02期

关键词：

down syndrome; fetus; prenatal screening; soft marker; ultrasound;

D O I：

10.1111/j.1479-828X.2008.00826.x

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Ultrasound soft markers are commonly reported at mid-trimester ultrasounds. Soft markers frequently arouse anxiety in the patient, her family, and the referring clinician. Recent publications have raised concerns that this anxiety may be unfounded. The significance of an echogenic intracardiac focus or choroid plexus cyst in particular is no longer certain. It may be time to discard these two markers; especially if they are reported in isolation and in a patient who is otherwise at low risk for aneuploidy.

引用

页码：137 / 141

页数：5

共 37 条

[31] Second trimester prenatal ultrasound for the detection of pregnancies at increased risk of Down syndrome [J].

Smith-Bindman, Rebecca ;

Chu, Philip ;

Goldberg, James D. .

PRENATAL DIAGNOSIS, 2007, 27 (06) :535-544

[32] Diagnostic performance of intracardiac echogenic foci for Down syndrome: A meta-analysis [J].

Sotiriadis, A ;

Makrydimas, G ;

Ioannidis, JPA .

OBSTETRICS AND GYNECOLOGY, 2003, 101 (05) :1009-1016

[33] Isolated fetal echogenic intracardiac foci or golf balls: is karyotyping for Down's syndrome indicated? [J].

Thilaganathan, B ;

Olawaiye, A ;

Sairam, S ;

Harrington, K .

BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 1999, 106 (12) :1294-1297

[34] Ethnic variation in the prevalence of echogenic intracardiac foci and the association with Down syndrome [J].

Tran, SH ;

Caughey, AB ;

Norton, ME .

ULTRASOUND IN OBSTETRICS & GYNECOLOGY, 2005, 26 (02) :158-161

[35] ISOLATED CHOROID-PLEXUS CYSTS - THE NEED FOR ROUTINE OFFER OF KARYOTYPING [J].

WALKINSHAW, SA ;

PILLING, D ;

SPRIGGS, A .

PRENATAL DIAGNOSIS, 1994, 14 (08) :663-667

[36] Fetal intracardiac echogenic foci: Current understanding and clinical significance [J].

Wax, JR ;

Mather, J ;

Steinfeld, JD ;

Ingardia, CJ .

OBSTETRICAL & GYNECOLOGICAL SURVEY, 2000, 55 (05) :303-311

[37] Ultrasonographic ''soft markers'' of fetal chromosomal defects - Detecting them may do more harm than good [J].

Whittle, M .

BRITISH MEDICAL JOURNAL, 1997, 314 (7085) :918-918

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