Time to reconsider our approach to echogenic intracardiac focus and choroid plexus cysts

被引：15
作者：
Bethune, Michael [1 ,2 ,3 ]
机构：
[1] Melbourne Ultrasound Women, Melbourne, Vic, Australia
[2] Royal Hosp Women, Ultrasound Dept, Melbourne, Vic, Australia
[3] Mercy Hosp Women, Dept Med Imaging, Melbourne, Vic, Australia
来源：
AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY | 2008年 / 48卷 / 02期
关键词：
down syndrome; fetus; prenatal screening; soft marker; ultrasound;
D O I：
10.1111/j.1479-828X.2008.00826.x
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Ultrasound soft markers are commonly reported at mid-trimester ultrasounds. Soft markers frequently arouse anxiety in the patient, her family, and the referring clinician. Recent publications have raised concerns that this anxiety may be unfounded. The significance of an echogenic intracardiac focus or choroid plexus cyst in particular is no longer certain. It may be time to discard these two markers; especially if they are reported in isolation and in a patient who is otherwise at low risk for aneuploidy.
引用
收藏
页码：137 / 141
页数：5
相关论文
共 37 条
[1]   Relationship of isolated fetal intracardiac echogenic focus to trisomy 21 at the-mid-trimester sonogram in women younger than 35 years [J].
Anderson, N ;
Jyoti, R .
ULTRASOUND IN OBSTETRICS & GYNECOLOGY, 2003, 21 (04) :354-358
[2]   Should sonographic screening for fetal Down syndrome be applied to low risk women? [J].
Benacerraf, BR .
ULTRASOUND IN OBSTETRICS & GYNECOLOGY, 2000, 15 (06) :451-455
[3]   SONOGRAPHIC DIAGNOSIS OF DOWN SYNDROME IN THE 2ND TRIMESTER [J].
BENACERRAF, BR ;
FRIGOLETTO, FD ;
LABODA, LA .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1985, 153 (01) :49-52
[4]   Literature Review and suggested protocol for managing ultrasound soft markers for Down syndrome: Thickened nuchal fold, echogenic bowel, shortened femur, shortened humerus, pyelectasis and absent or hypoplastic nasal bone [J].
Bethune, M. .
AUSTRALASIAN RADIOLOGY, 2007, 51 (03) :218-225
[5]   Management options for echogenic intracardiac focus and choroid plexus cysts: A review including Australian Association of Obstetrical and Gynaecological Ultrasonologists consensus statement [J].
Bethune, M. .
AUSTRALASIAN RADIOLOGY, 2007, 51 (04) :324-329
[6]   6-year experience of prenatal diagnosis in an unselected population in Oxford, UK [J].
Boyd, PA ;
Chamberlain, P ;
Hicks, NR .
LANCET, 1998, 352 (9140) :1577-1581
[7]   An isolated intracardiac echogenic focus as a marker for aneuploidy [J].
Bradley, KE ;
Santulli, TS ;
Gregory, KD ;
Herbert, W ;
Carlson, DE ;
Platt, LD .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2005, 192 (06) :2021-2026
[8]   Choroid plexus cysts: Not associated with Down syndrome [J].
Bromley, B ;
Lieberman, E ;
Benacerraf, BR .
ULTRASOUND IN OBSTETRICS & GYNECOLOGY, 1996, 8 (04) :232-235
[9]   Fetal nose bone length - A marker for Down syndrome in the second trimester [J].
Bromley, B ;
Lieberman, E ;
Shipp, TD ;
Benacerraf, BR .
JOURNAL OF ULTRASOUND IN MEDICINE, 2002, 21 (12) :1387-1394
[10]   The genetic sonogram - A method of risk assessment for Down syndrome in the second trimester [J].
Bromley, B ;
Lieberman, E ;
Shipp, TD ;
Benacerraf, BR .
JOURNAL OF ULTRASOUND IN MEDICINE, 2002, 21 (10) :1087-1096
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