The kth power of a graph G = (V, E), G(k), is the graph whose vertex set is V and in which two distinct vertices are adjacent if and only if their distance in G is at most k. This article proves various eigenvalue bounds for the independence number and chromatic number of G(k) which purely depend on the spectrum of G, together with a method to optimize them. Our bounds for the k-independence number also work for its quantum counterpart, which is not known to be a computable parameter in general, thus justifying the use of integer programming to optimize them. Some of the bounds previously known in the literature follow as a corollary of our main results. Infinite families of graphs where the bounds are sharp are presented as well. (C) 2021 Published by Elsevier B.V.