Electrospun Medicated Nanofibers for Wound Healing: Review

被引:222
作者
Liu, Xinkuan [1 ]
Xu, Haixia [1 ]
Zhang, Mingxin [1 ]
Yu, Deng-Guang [1 ,2 ]
机构
[1] Univ Shanghai Sci & Technol, Sch Mat Sci & Engn, Shanghai 200093, Peoples R China
[2] Shanghai Engn Technol Res Ctr High Performance Me, Shanghai 200093, Peoples R China
基金
上海市自然科学基金;
关键词
wound dressing; electrospinning; nanostructure; nanocomposite; ANTIBACTERIAL ACTIVITY; CHITOSAN MEMBRANES; SILK FIBROIN; IN-VITRO; DRESSINGS; DELIVERY; DRUG; FABRICATION; SCAFFOLD; HYDROGEL;
D O I
10.3390/membranes11100770
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
With the increasing demand for wound care and treatment worldwide, traditional dressings have been unable to meet the needs of the existing market due to their limited antibacterial properties and other defects. Electrospinning technology has attracted more and more researchers' attention as a simple and versatile manufacturing method. The electrospun nanofiber membrane has a unique structure and biological function similar to the extracellular matrix (ECM), and is considered an advanced wound dressing. They have significant potential in encapsulating and delivering active substances that promote wound healing. This article first discusses the common types of wound dressing, and then summarizes the development of electrospun fiber preparation technology. Finally, the polymers and common biologically active substances used in electrospinning wound dressings are summarized, and portable electrospinning equipment is also discussed. Additionally, future research needs are put forward.
引用
收藏
页数:22
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