Choroid plexus carcinoma in an adolescent male: a case report

被引:3
作者
Jameel, Patel Zeeshan [1 ]
Varma, Ashish [1 ]
Kumari, Pooja [1 ]
Vagha, Keta [1 ]
Vagha, Jayant [1 ]
Damke, Sachin [1 ]
机构
[1] Jawaharlal Nehru Med Coll, Dept Paediat, Wardha 442001, Maharashtra, India
关键词
Choroid plexus carcinoma; Brain tumor; Gross total resection; CHEMOTHERAPY; SURVIVAL; METAANALYSIS; RADIATION; CHILDREN; SURGERY; THERAPY; TUMORS;
D O I
10.1186/s13256-021-02801-w
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Introduction/background Although central nervous system tumors are the most common etiology of malignancies in the pediatric age group, choroid plexus carcinomas are rare, with an annual incidence rate of 0.10 per 100,000 children. Case presentation We report the case of an adolescent male belonging to central India who had presented with a history of persistent headache, projectile vomiting, neck stiffness, and an episode of generalized tonic-clonic seizure. Neurological examination was suggestive of a space-occupying lesion. Further neuroimaging was suggestive of a large left-sided choroid plexus carcinoma, later confirmed on pathological examination. Gross total resection was achieved and followed by radiation therapy. His recovery was satisfactory without any major events despite suffering from such a malignancy with a poor prognosis. Conclusion In the absence of a global consensus on choroid plexus carcinoma management, our patient underwent a successful gross total resection and received postoperative radiotherapy. He made a satisfactory recovery with a further plan to review with gadolinium-enhanced neuroimaging at a later date. We conclude that, when possible, achieving gross total resection is of utmost importance.
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页数:5
相关论文
共 15 条
[1]  
Gopal P, 2008, ARCH PATHOL LAB MED, V132, P1350, DOI 10.1043/1543-2165(2008)132[1350:CPC]2.0.CO
[2]  
2
[3]   Use of ifosfamide, carboplatin, and etoposide chemotherapy in choroid plexus carcinoma Clinical article [J].
Lafay-Cousin, Lucie ;
Mabbott, Donald J. ;
Halliday, William ;
Taylor, Michael D. ;
Tabori, Uri ;
Kamaly-Asl, Ian D. ;
Kulkarni, Abhaya V. ;
Bartels, Ute ;
Greenberg, Mark ;
Bouffet, Eric .
JOURNAL OF NEUROSURGERY-PEDIATRICS, 2010, 5 (06) :615-621
[4]   Choroid Plexus Tumors in Children: A Population-Based Study [J].
Lam, Sandi ;
Lin, Yimo ;
Cherian, Jacob ;
Qadri, Usama ;
Harris, Dominic A. ;
Melkonian, Stephanie ;
Jea, Andrew .
PEDIATRIC NEUROSURGERY, 2013, 49 (06) :331-338
[5]   The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary [J].
Louis, David N. ;
Perry, Arie ;
Reifenberger, Guido ;
von Deimling, Andreas ;
Figarella-Branger, Dominique ;
Cavenee, Webster K. ;
Ohgaki, Hiroko ;
Wiestler, Otmar D. ;
Kleihues, Paul ;
Ellison, David W. .
ACTA NEUROPATHOLOGICA, 2016, 131 (06) :803-820
[6]   Effect of Surgery, Adjuvant Therapy, and Other Prognostic Factors on Choroid Plexus Carcinoma: A Systematic Review and Individual Patient Data Analysis [J].
Mallick, Supriya ;
Benson, Rony ;
Melgandi, Wineeta ;
Rath, Goura K. .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2017, 99 (05) :1199-1206
[7]   THE IMPACT OF RADIOTHERAPY FIELDS IN THE TREATMENT OF PATIENTS WITH CHOROID PLEXUS CARCINOMA [J].
Mazloom, Ali ;
Wolff, Johannes E. ;
Paulino, Arnold C. .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2010, 78 (01) :79-84
[8]  
Ostrom QT, 2014, NEURO-ONCOLOGY, V16, P1, DOI [10.1093/neuonc/nou223, 10.1093/neuonc/nox158, 10.1093/neuonc/nou327, 10.1093/neuonc/nov189]
[9]   Neoadjuvant chemotherapy reduces blood loss during the resection of pediatric choroid plexus carcinomas [J].
Schneider, Christian ;
Kamaly-Asl, Ian ;
Ramaswamy, Vijay ;
Lafay-Cousin, Lucie ;
Kulkarni, Abhaya V. ;
Rutka, James T. ;
Remke, Marc ;
Coluccia, Daniel ;
Tabori, Uri ;
Hawkins, Cynthia ;
Bouffet, Eric ;
Taylor, Michael D. .
JOURNAL OF NEUROSURGERY-PEDIATRICS, 2015, 16 (02) :126-133
[10]   Effects of adjuvant chemotherapy and radiation on overall survival in children with choroid plexus carcinoma [J].
Sun, Matthew Z. ;
Ivan, Michael E. ;
Oh, Michael C. ;
Delance, Arthur R. ;
Clark, Aaron J. ;
Safaee, Michael ;
Oh, Taemin ;
Kaur, Gurvinder ;
Molinaro, Annette ;
Gupta, Nalin ;
Parsa, Andrew T. .
JOURNAL OF NEURO-ONCOLOGY, 2014, 120 (02) :353-360