Polypoidal Choroidal Vasculopathy Diagnosis and Neovascular Activity Evaluation Using Optical Coherence Tomography Angiography

被引:10
作者
Azar, Georges [1 ]
Vasseur, Vivien [2 ]
Lahoud, Corinne [3 ]
Favard, Catherine [2 ]
De Bats, Flore [4 ]
Cochereau, Isabelle [1 ]
Yachvitz, Amelie [2 ]
Mauget-Faysse, Martine [2 ]
机构
[1] Rothschild Ophthalmol Fdn, Anterior Segment Dept, 25 Rue Manin, F-75940 Paris 19, France
[2] Rothschild Ophthalmol Fdn, Ctr Clin Invest, 25 Rue Manin, F-75940 Paris 19, France
[3] Holy Spirit Univ Kaslik USEK, Fac Med, Kaslik, Lebanon
[4] Val dOuest Clin, Pole Vis Ctr, 39 Chemin Vernique, F-69130 Ecully, France
关键词
CLASSIFICATION;
D O I
10.1155/2021/1637377
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Purpose. To examine choroidal neovascularization (CNV) characteristics in patients with exudative age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV), using swept-source optical coherence tomography angiography (SS-OCTA), and investigate agreement with OCT B-scan, fundus fluorescein angiography (FFA), and indocyanine green angiography (ICGA) by two different examiners. Methods. This is a retrospective multicentric study that involved patients with a history of AMD and PCV. Examiner A, who had access to OCTA, B-scan OCT, FFA, and ICGA imaging, had to differentiate between AMD and PCV, study the activity of AMD using Coscas' criteria (active vs. quiescent), and categorize PCV subtypes, while examiner B had only access to OCTA. Then, the diagnostic concordance was assessed between both examiners. Results. A total of 27 patients (11 females (40.7%) and 16 males (59.3%), P=0.231) were included in the analysis. Among those, 13 patients presented with neovascular AMD and 14 patients with PCV. There were 92.3% of correct answers regarding appropriate diagnosis and lesion characterization among AMD patients, against 61.5% of correct answers among PCV patients. The overall interrater reliability agreement between examiners, using Cohen's kappa coefficient (kappa) was 0.70 (0.5082-0.8916). Disagreement was found with one active AMD misdiagnosed as inactive AMD, three inactive PCV misdiagnosed as inactive AMD, and one inactive PCV misdiagnosed as active AMD. Conclusion. SS-OCTA alone remains limited in some specific phenotypes of PCV, which suggests the ongoing role of B-scan OCT associated with FFA and ICGA in the diagnosis of these conditions.
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页数:7
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共 22 条
  • [1] POLYPOIDAL CHOROIDAL VASCULOPATHY UPON OPTICAL COHERENCE TOMOGRAPHIC ANGIOGRAPHY
    Chan, Szy Yann
    Wang, Qian
    Wang, Ya Xing
    Shi, Xue Hui
    Jonas, Jost B.
    Bin Wei, Wen
    [J]. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 2018, 38 (06): : 1187 - 1194
  • [2] IMPROVED DETECTION AND DIAGNOSIS OF POLYPOIDAL CHOROIDAL VASCULOPATHY USING A COMBINATION OF OPTICAL COHERENCE TOMOGRAPHY AND OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
    Cheung, Chui Ming Gemmy
    Yanagi, Yasuo
    Akiba, Masahiro
    Tan, Anna
    Mathur, Ranjana
    Chan, Choi Mun
    Yeo, Ian
    Wong, Tien Y.
    [J]. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 2019, 39 (09): : 1655 - 1663
  • [3] Polypoidal Choroidal Vasculopathy Definition, Pathogenesis, Diagnosis, and Management
    Cheung, Chui Ming Gemmy
    Lai, Timothy Y. Y.
    Ruamviboonsuk, Paisan
    Chen, Shih-Jen
    Chen, Youxin
    Freund, K. Bailey
    Gomi, Fomi
    Koh, Adrian H.
    Lee, Won-Ki
    Wong, Tien Yin
    [J]. OPHTHALMOLOGY, 2018, 125 (05) : 708 - 724
  • [4] CHARACTERIZATION AND DIFFERENTIATION OF POLYPOIDAL CHOROIDAL VASCULOPATHY USING SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
    Cheung, Chui Ming Gemmy
    Yanagi, Yasuo
    Mohla, Aditi
    Lee, Shu Yen
    Mathur, Ranjana
    Chan, Choi Mun
    Yeo, Ian
    Wong, Tien Yin
    [J]. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 2017, 37 (08): : 1464 - 1474
  • [5] Optical Coherence Tomography Angiography for Assessment of the 3-Dimensional Structures of Polypoidal Choroidal Vasculopathy
    Chi, Yu-Tien
    Yang, Chang-Hao
    Cheng, Cheng-Kuo
    [J]. JAMA OPHTHALMOLOGY, 2017, 135 (12) : 1310 - 1316
  • [6] Optical coherence tomography angiography in exudative age-related macular degeneration: a predictive model for treatment decisions
    Coscas, Florence
    Lupidi, Marco
    Boulet, Jean Francois
    Sellam, Alexandre
    Cabral, Diogo
    Serra, Rita
    Francais, Catherine
    Souied, Eric H.
    Coscas, Gabriel
    [J]. BRITISH JOURNAL OF OPHTHALMOLOGY, 2019, 103 (09) : 1342 - 1346
  • [7] Toward a Specific Classification of Polypoidal Choroidal Vasculopathy: Idiopathic Disease or Subtype of Age-Related Macular Degeneration
    Coscas, Gabriel
    Lupidi, Marco
    Coscas, Florence
    Benjelloun, Faycal
    Zerbib, Jennifer
    Dirani, Ali
    Semoun, Oudy
    Souied, Eric H.
    [J]. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2015, 56 (05) : 3187 - 3195
  • [8] OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY VERSUS TRADITIONAL MULTIMODAL IMAGING IN ASSESSING THE ACTIVITY OF EXUDATIVE AGE-RELATED MACULAR DEGENERATION A New Diagnostic Challenge
    Coscas, Gabriel J.
    Lupidi, Marco
    Coscas, Florence
    Cagini, Carlo
    Souied, Eric H.
    [J]. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 2015, 35 (11): : 2219 - 2228
  • [9] SENSITIVITY AND SPECIFICITY OF DETECTING POLYPOIDAL CHOROIDAL VASCULOPATHY WITH EN FACE OPTICAL COHERENCE TOMOGRAPHY AND OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
    de Carlo, Talisa E.
    Kokame, Gregg T.
    Kaneko, Kyle N.
    Lian, Rebecca
    Lai, James C.
    Wee, Raymond
    [J]. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 2019, 39 (07): : 1343 - 1352
  • [10] Characteristics of type 1 and 2 CNV in exudative AMD in OCT-Angiography
    Farecki, Marie-Louise
    Gutfleisch, Matthias
    Faatz, Henrik
    Rothaus, Kai
    Heimes, Britta
    Spital, Georg
    Lommatzsch, Albrecht
    Pauleikhoff, Daniel
    [J]. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2017, 255 (05) : 913 - 921