Management of inflammatory bowel disease in the COVID-19 era

被引:16
作者
Kim, Kyeong Ok [1 ]
Jang, Byung Ik [1 ]
机构
[1] Yeungnam Univ, Div Gastroenterol & Hepatol, Dept Internal Med, Coll Med, 170 Hyeonchung Ro, Daegu 42415, South Korea
关键词
Inflammatory bowel disease; Coronavirus; COVID-19; SARS-CoV-2; ULCERATIVE-COLITIS; BIOLOGIC DRUGS; SAFETY PROFILE; RISK-FACTORS; SARS-COV-2; THERAPY; INFECTIONS; ACE2; IBD; EXPRESSION;
D O I
10.5217/ir.2020.00156
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
During the coronavirus disease 2019 (COVID-19) pandemic, many unpredictable changes have occurred in the medical field. Risk of COVID-19 does not seem to increase in patients with inflammatory bowel disease (IBD) considering based on current reports. Current medications for IBD do not increase this risk; on the contrary, some of these might be used as therapeutics against COVID-19 and are under clinical trial. Unless the patients have confirmed COVID-19 and severe pneumonia or a high oxygen demand, medical treatment should be continued during the pandemic, except for the use of high-dose corticosteroids. Adherence to general recommendations such as social distancing, wearing facial masks, and vaccination, especially for pneumococcal infections and influenza, is also required. Patients with COVID-19 need to be withhold immunomodulators or biologics for at least 2 weeks and treated based on both IBD and COVID-19 severity. Prevention of IBD relapse caused by sudden medication interruption is important because negative outcomes associated with disease flare up, such as corticosteroid use or hospitalization, are much riskier than medications. The outpatient clinic and infusion center for biologics need to be reserved safe spaces, and endoscopy or surgery should be considered in urgent cases only.
引用
收藏
页码:3 / 10
页数:8
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