Recent developments in neuropeptide Y receptor modulators

被引：3
作者：
Stamford, AW [1 ]
Hwa, J [1 ]
van Heek, M [1 ]
机构：
[1] Schering Plough Corp, Inst Res, Kenilworth, NJ 07033 USA
来源：
ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 38 | 2003年 / 38卷
关键词：
D O I：
10.1016/S0065-7743(03)38008-X
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：61 / 70
页数：10
相关论文
共 71 条
[1]   Hypothalamic Y2 receptors regulate bone formation [J].
Baldock, PA ;
Sainsbury, A ;
Couzens, M ;
Enriquez, RF ;
Thomas, GP ;
Gardiner, EM ;
Herzog, H .
JOURNAL OF CLINICAL INVESTIGATION, 2002, 109 (07) :915-921
[2]   Behavioral characterization of neuropeptide Y knockout mice [J].
Bannon, AW ;
Seda, J ;
Carmouche, M ;
Francis, JM ;
Norman, MH ;
Karbon, B ;
McCaleb, ML .
BRAIN RESEARCH, 2000, 868 (01) :79-87
[3]   Gut hormone PYY3-36 physiologically inhibits food intake [J].
Batterham, RL ;
Cowley, MA ;
Small, CJ ;
Herzog, H ;
Cohen, MA ;
Dakin, CL ;
Wren, AM ;
Brynes, AE ;
Low, MJ ;
Ghatei, MA ;
Cone, RD ;
Bloom, SR .
NATURE, 2002, 418 (6898) :650-654
[4]   Induction of hypertrophic responsiveness of cardiomyocytes to neuropeptide Y in response to pressure overload [J].
Bell, D ;
Allen, AR ;
Kelso, EJ ;
Balasubramaniam, A ;
McDermott, BJ .
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2002, 303 (02) :581-591
[5]   Discovery and optimization of a series of carbazole ureas as NPY5 antagonists for the treatment of obesity [J].
Block, MH ;
Boyer, S ;
Brailsford, W ;
Brittain, DR ;
Carroll, D ;
Chapman, S ;
Clarke, DS ;
Donald, CS ;
Foote, KM ;
Godfrey, L ;
Ladner, A .
JOURNAL OF MEDICINAL CHEMISTRY, 2002, 45 (16) :3509-3523
[6]   Functional effects of neuropeptide Y receptors on blood flow and nitric oxide levels in the human nose [J].
Cervin, A ;
Önnerfält, J ;
Edvinsson, L ;
Grundemar, L .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1999, 160 (05) :1724-1728
[7]   NEUROPEPTIDE-Y AND HUMAN PANCREATIC-POLYPEPTIDE STIMULATE FEEDING-BEHAVIOR IN RATS [J].
CLARK, JT ;
KALRA, PS ;
CROWLEY, WR ;
KALRA, SP .
ENDOCRINOLOGY, 1984, 115 (01) :427-429
[8]   Food intake in free-feeding and energy-deprived lean rats is mediated by the neuropeptide Y5 receptor [J].
Criscione, L ;
Rigollier, P ;
Batzl-Hartmann, C ;
Rüeger, H ;
Stricker-Krongrad, A ;
Wyss, P ;
Brunner, L ;
Whitebread, S ;
Yamaguchi, Y ;
Gerald, C ;
Heurich, RO ;
Walker, MW ;
Chiesi, M ;
Schilling, W ;
Hofbauer, KG ;
Levens, N .
JOURNAL OF CLINICAL INVESTIGATION, 1998, 102 (12) :2136-2145
[9]   Food intake inhibition and reduction in body weight gain in lean and obese rodents treated with GW438014A, a potent and selective NPY-Y5 receptor antagonist [J].
Daniels, AJ ;
Grizzle, MK ;
Wiard, RP ;
Matthews, JE ;
Heyer, D .
REGULATORY PEPTIDES, 2002, 106 (1-3) :47-54
[10]   Small-molecule neuropeptide YY5 antagonists [J].
Dax, SL .
DRUGS OF THE FUTURE, 2002, 27 (03) :273-287
12345678