Phase 1 study of CB-103, a novel first-in-class inhibitor of the CSL-NICD gene transcription factor complex in human cancers.

被引：23

作者：

Lopez Miranda, Elena

Stathis, Anastasios

Hess, Dagmar

Racca, Fabricio

Quon, Doris

Rodon, Jordi

Santa Gadea, Omar Saavedra

Perez Garcia, Jose Manuel

Nuciforo, Paolo

Vivancos, Ana

Cortes, Javier

Ferrarotto, Renata

Schonborn-Kellenberger, Oliver

Vigolo, Michele

Bobadilla, Maria

Beni, Laura

Lehal, Rajwinder

Bauer, Michael Pascal

Vogl, Florian D.

Garralda, Elena

机构：

[1] Hosp Univ Ramon y Cajal, Med Oncol, Madrid, Spain

[2] Oncol Inst Southern Switzerland, Bellinzona, Switzerland

[3] Kantonsspital St Gallen, Dept Med Oncol, St Gallen, Switzerland

[4] Hosp Quironsalud Barcelona, IOB Inst Oncol Barcelona & Madrid, Barcelona, Spain

[5] Sarcoma Oncol Res Ctr, Santa Monica, CA USA

[6] Univ Texas MD Anderson Canc Ctr, Dept Invest Canc Therapeut, Houston, TX 77030 USA

[7] Vall dHebron Inst Oncol VHIO, Dept Med Oncol, Barcelona, Spain

[8] Quiron Hosp, Int Breast Canc Ctr, Barcelona, Spain

[9] Vall dHebron Inst Oncol VHIO, Mol Oncol Grp, Barcelona, Spain

[10] Vall dHebron Inst Oncol VHIO, Canc Genom, Barcelona, Spain

[11] IOB Inst Oncol, Quironsalud Grp, Barcelona, Spain

[12] Vall dHebron Inst Oncol VHIO, Barcelona, Spain

[13] Univ Texas MD Anderson Canc Ctr, Thorac Head & Neck Med Oncol, Houston, TX 77030 USA

[14] Cogitars GmbH, Heidelberg, Germany

[15] Cellestia Biotech AG, R&D, Epalinges, Switzerland

[16] Cellestia Biotech AG, Basel, Switzerland

[17] Vall dHebron Univ Hosp, Early Drug Dev Unit, Barcelona, Spain

[18] Inst Oncol VHIO, Barcelona, Spain

[19] Vall dHebron Univ Hosp HUVH, Med Oncol, Barcelona, Spain

来源：

JOURNAL OF CLINICAL ONCOLOGY | 2021年 / 39卷 / 15期

关键词：

D O I：

10.1200/JCO.2021.39.15_suppl.3020

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

3020

引用

页数：2