Biomarker-Based Management of AKI: Fact or Fantasy?

被引:15
作者
Ostermann, Marlies [1 ]
Karsten, Emma [2 ]
Lumlertgul, Nuttha [1 ,3 ,4 ,5 ]
机构
[1] Kings Coll London, Dept Crit Care, Guys & St Thomas NHS Fdn Trust, London, England
[2] Guys & St Thomas Fdn Trust, Emergency Dept, London, England
[3] King Chulalongkorn Mem Hosp, Div Nephrol, Dept Internal Med, Bangkok, Thailand
[4] King Chulalongkorn Mem Hosp, Excellence Ctr Crit Care Nephrol, Bangkok, Thailand
[5] Chulalongkorn Univ, Res Unit Crit Care Nephrol, Bangkok, Thailand
关键词
Acute kidney injury; Biomarkers; ACUTE KIDNEY INJURY; DEFINITIONS;
D O I
10.1159/000518365
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
New biomarkers for acute kidney injury (AKI) have improved our understanding of the etiology and pathogenesis of AKI. Depending on their origin, function, and kinetic profile, biomarkers have a role in screening, diagnosis, prognostication, and monitoring of AKI. This offers opportunities to improve the management of AKI, but concerns and limitations remain. In this review, we summarize the current role of new AKI biomarkers in the management of AKI and outline some of the ongoing limitations and challenges.
引用
收藏
页码:295 / 301
页数:7
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