Characterization of chitosan-lysine surfactant bioactive coating on silicone substrate

被引：16

作者：

Ajdnik, Urban ^{[1
]}

Finsgar, Matjaz ^{[2
]}

Zemljic, Lidija Fras ^{[1
]}

机构：

[1] Univ Maribor, Inst Engn Mat & Design, Fac Mech Engn, Smetanova Ul 17, SLO-2000 Maribor, Slovenia

[2] Univ Maribor, Fac Chem & Chem Engn, Smetanova Ul 17, SLO-2000 Maribor, Slovenia

来源：

CARBOHYDRATE POLYMERS | 2020年 / 232卷

关键词：

Chitosan; Lysine surfactant; Polydimethylsiloxane; Bioactive coating; QCM-D; Surface analysis; ETHYL(HYDROXYETHYL) CELLULOSE; CATIONIC SURFACTANT; HYALURONIC-ACID; CROSS-LINKING; NANOPARTICLES; POLYDIMETHYLSILOXANE; BIOPOLYMERS; DOXORUBICIN; HEMOLYSIS; MIXTURES;

D O I：

10.1016/j.carbpol.2019.115817

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Chitosan (Chi) and anionic surfactant derived from lysine (77KS) were used to prepare a novel bioactive coating and as a drug delivery system for amoxicillin (AMOX) on a model polydimethylsiloxane (PDMS) surface. The bioactive coating was formulated as polyelectrolyte-surfactant complex (PESC). Aggregation behaviour between the cationic Chi and oppositely charged 77KS in bulk was analysed using turbidity and.-potential measurement. Furthermore, the adsorption and stability of the formulations were evaluated using quartz crystal microbalance with dissipation (QCM-D). The effect of the ionic strength and of the ultraviolet/ozone (UVO) activation of the PDMS films on the adsorption behaviour of the PESC complex was also examined. QCM-D monitoring showed stable adsorption of bare and AMOX-loaded complex on non-activated PDMS films, while the coating on UVO-activated PDMS samples desorbed after the rinsing step. Finally, X-ray photoelectron spectroscopy and time-of-flight secondary ion mass spectrometry confirmed successful and homogenously distributed compounds.

引用

页数：10

共 67 条

[1] Novel composite blend microbeads of sodium alginate coated with chitosan for controlled release of amoxicillin [J].

Angadi, Sudha C. ;

Manjeshwar, Lata S. ;

Aminabhavi, Tejraj M. .

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2012, 51 (1-2) :45-55

[2] The Adsorption Behavior of Ionic Surfactants and Their Mixtures with Nonionic Polymers and with Polyelectrolytes of Opposite Charge at the Air-Water Interface [J].

Bahramian, Alireza ;

Thomas, Robert K. ;

Penfold, Jeffrey .

JOURNAL OF PHYSICAL CHEMISTRY B, 2014, 118 (10) :2769-2783

[3] Cross-Linking the Surface of Cured Polydimethylsiloxane via Hyperthemal Hydrogen Projectile Bombardment [J].

Bao, Chao ;

Xu, Ke-Qin ;

Tang, Chang-Yu ;

Lau, Woon-ming ;

Yin, Cong-Bin ;

Zhu, Yan ;

Mei, Jun ;

Lee, Jonathan ;

Hui, David ;

Nie, Heng-Yong ;

Liu, Yu .

ACS APPLIED MATERIALS & INTERFACES, 2015, 7 (16) :8515-8524

[4] IR, Raman, SERS and DFT study of amoxicillin [J].

Bebu, Andreea ;

Szabo, Laszlo ;

Leopold, Nicolae ;

Berindean, Catalin ;

David, Leontin .

JOURNAL OF MOLECULAR STRUCTURE, 2011, 993 (1-3) :52-56

[5]

Brac M., 2018, BIOACTIVE FUNCTIONAL, VXVI, P75

[6]

Bracic M., 2019, MATERIALS, V16, P1

[7] Interaction of Sodium Hyaluronate with a Biocompatible Cationic Surfactant from Lysine: A Binding Study [J].

Bracic, Matej ;

Hansson, Per ;

Perez, Lourdes ;

Zemljic, Lidija F. ;

Kogej, Ksenija .

LANGMUIR, 2015, 31 (44) :12043-12053

[8] A novel synergistic formulation between a cationic surfactant from lysine and hyaluronic acid as an antimicrobial coating for advanced cellulose materials [J].

Bracic, Matej ;

Perez, Lourdes ;

Infante Martinez-Pardo, Rosa ;

Kogej, Ksenija ;

Hribernik, Silvo ;

Sauperl, Olivera ;

Zemljic, Lidija Fras .

CELLULOSE, 2014, 21 (04) :2647-2663

[9] Preparation of PDMS ultrathin films and patterned surface modification with cellulose [J].

Bracic, Matej ;

Mohan, Tamilselvan ;

Kargl, Rupert ;

Griesser, Thomas ;

Hribernik, Silvo ;

Koestler, Stefan ;

Stana-Kleinschek, Karin ;

Fras-Zemljic, Lidija .

RSC ADVANCES, 2014, 4 (23) :11955-11961

[10] Morphology, Thermal Behavior, and Stability of Self-Assembled Supramolecular Tubules from Lysine-Based Surfactants [J].

Brito, Rodrigo O. ;

Oliveira, Isabel S. ;

Araujo, Maria J. ;

Marques, Eduardo F. .

JOURNAL OF PHYSICAL CHEMISTRY B, 2013, 117 (32) :9400-9411

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