MIPOMERSEN, AN apo B SYNTHESIS INHIBITOR, PREFERENTIALLY REDUCES SMALL LDL PARTICLE NUMBER AND INCREASES LDL PARTICLE SIZE IN HoFH PATIENTS

被引：4

作者：

Cromwell, W. ^{[1
]}

Santos, R. ^{[2
]}

Blom, D. ^{[3
]}

Marais, A. D. ^{[3
]}

Charng, M. -J. ^{[4
,5
]}

Lachmann, R. ^{[6
]}

Gaudet, D. ^{[7
]}

Tan, J. -L. ^{[8
]}

Tribble, D. ^{[9
]}

Flaim, J. ^{[9
]}

Chasan-Taber, S. ^{[10
]}

Donovan, J. ^{[10
]}

Raal, F. ^{[11
]}

机构：

[1] Presbyterian Cardiovasc Inst, Div Atherosclerosis & Lipoprotein Disorders, Charlotte, NC USA

[2] Univ Sao Paulo, Heart Inst inCor, Sao Paulo, Brazil

[3] Univ Cape Town, Dept Med, Div Lipidol, ZA-7925 Cape Town, South Africa

[4] Taichung Vet Gen Hosp, Dept Cardiol, Taipei, Taiwan

[5] Natl Yang Ming Univ, Taipei 112, Taiwan

[6] Univ Coll London Hosp, Charles Dent Metab Unit, London, England

[7] ECOGENE 21 Clin Res Ctr & Lipid Clin, Chicoutimi, PQ, Canada

[8] Natl Heart Ctr, Singapore, Singapore

[9] Isis Pharmaceut Inc, Carlsbad, CA USA

[10] Genzyme Corp, Cambridge, MA USA

[11] Univ Witwatersrand, Dept Med, ZA-2001 Johannesburg, South Africa

来源：

关键词：

D O I：

10.1016/S1567-5688(10)70498-0

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

P431

引用

页码：107 / 108

页数：2