Chitosan based metallic nanocomposite scaffolds as antimicrobial wound dressings

被引：204
作者：
Mohandas, Annapoorna [1 ]
Deepthi, S. [1 ]
Biswas, Raja [1 ]
Jayakumar, R. [1 ]
机构：
[1] Amrita Vishwa Vidyapeetham, Amrita Inst Med Sci & Res Ctr, Ctr Nanosci & Mol Med, Kochi 682041, Kerala, India
来源：
BIOACTIVE MATERIALS | 2018年 / 3卷 / 03期
关键词：
Antimicrobial Chitosan nanocomposities; Silver; Zinc oxide; Gold; Copper; Wound healing; TITANIUM-DIOXIDE NANOPARTICLES; ZINC-OXIDE NANOPARTICLES; SILVER NANOPARTICLES; COPPER NANOPARTICLES; ANTIBACTERIAL ACTIVITY; IN-VITRO; HEALING ACTIVITY; TOXICITY; GOLD; MECHANISMS;
D O I：
10.1016/j.bioactmat.2017.11.003
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Chitosan based nanocomposite scaffolds have attracted wider applications in medicine, in the area of drug delivery, tissue engineering and wound healing. Chitosan matrix incorporated with nanometallic components has immense potential in the area of wound dressings due to its antimicrobial properties. This review focuses on the different combinations of Chitosan metal nanocomposites such as Chitosan/nAg, Chitosan/nAu, Chitosan/nCu, Chitosan/nZnO and Chitosan/nTiO(2) towards enhancement of healing or infection control with special reference to the antimicrobial mechanism of action and toxicity. (c) 2017 The Authors. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
引用
收藏
页码：267 / 277
页数：11
相关论文
共 104 条
[1]   Antimicrobial wound dressing nanofiber mats from multicomponent (chitosan/silver-NPs/polyvinyl alcohol) systems [J].
Abdelgawad, Abdelrahman M. ;
Hudson, Samuel M. ;
Rojas, Orlando J. .
CARBOHYDRATE POLYMERS, 2014, 100 :166-178
[2]   Effect of Gold Nanoparticle Aggregation on Cell Uptake and Toxicity [J].
Albanese, Alexandre ;
Chan, Warren C. W. .
ACS NANO, 2011, 5 (07) :5478-5489
[3]   Chitosan-hyaluronic acid/nano silver composite sponges for drug resistant bacteria infected diabetic wounds [J].
Anisha, B. S. ;
Biswas, Raja ;
Chennazhi, K. P. ;
Jayakumar, R. .
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2013, 62 :310-320
[4]   Chitin and chitosan in selected biomedical applications [J].
Anitha, A. ;
Sowmya, S. ;
Kumar, P. T. Sudheesh ;
Deepthi, S. ;
Chennazhi, K. P. ;
Ehrlich, H. ;
Tsurkan, M. ;
Jayakumar, R. .
PROGRESS IN POLYMER SCIENCE, 2014, 39 (09) :1644-1667
[5]   Biochemical properties of Hemigraphis alternata incorporated chitosan hydrogel scaffold [J].
Annapoorna, M. ;
Kumar, P. T. Sudheesh ;
Lakshman, Lakshmi R. ;
Lakshmanan, Vinoth-Kumar ;
Nair, Shantikumar V. ;
Jayakumar, R. .
CARBOHYDRATE POLYMERS, 2013, 92 (02) :1561-1565
[6]   In vivo evaluation of chitosan-PVP-titanium dioxide nanocomposite as wound dressing material [J].
Archana, D. ;
Singh, Brijesh K. ;
Dutta, Joydeep ;
Dutta, P. K. .
CARBOHYDRATE POLYMERS, 2013, 95 (01) :530-539
[7]   Evaluation of chitosan nano dressing for wound healing: Characterization, in vitro and in vivo studies [J].
Archana, D. ;
Dutta, Joydeep ;
Dutta, P. K. .
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2013, 57 :193-203
[8]   Preparation, characterization and evaluation of biocomposite films containing chitosan and sago starch impregnated with silver nanoparticles [J].
Arockianathan, P. Marie ;
Sekar, S. ;
Kumaran, B. ;
Sastry, T. P. .
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2012, 50 (04) :939-946
[9]   Cytotoxicity and Genotoxicity of Silver Nanoparticles in Human Cells [J].
AshaRani, P. V. ;
Mun, Grace Low Kah ;
Hande, Manoor Prakash ;
Valiyaveettil, Suresh .
ACS NANO, 2009, 3 (02) :279-290
[10]  
Ashkani-Esfahani S., 2012, J CYTOL HISTOL, V3
12345678910