Heterocyclic systems containing bridgehead nitrogen atom: Synthesis and bio-activity of imidazo [1,2-a]-s-triazolo [3,4-b][1,3,4]-thiadiazoles - A novel heterocyclic system

被引：0

作者：

Mohan, J ^{[1
]}

Kumar, V ^{[1
]}

Khattar, D ^{[1
]}

机构：

[1] Maharshi Dayanand Univ, Dept Chem, Rohtak 124001, Haryana, India

来源：

INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 1998年 / 8卷 / 01期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A facile synthesis of 7-aryl-3-n-propyl-imidazo [1,2-a]-s- triazolo [3,4-b][1,3,4]-thiadiazole (3) has been achieved by the condensation of 3-n-propyl-4-amino-5-propyl-s-triazole(1) with cyanogen bromide to yield 6-amino-3-propyl-s-triazolo [3,4-b]-[1,3,4]thiadiazole (2) followed by treatment with alpha-haloketones. The structures (3) were supported by IR and PMR spectral data. The antibacterial and antifungal activity of the system have also been evaluated.

引用

页码：73 / 74

页数：2

共 50 条

[21] SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF s-TRIAZOLO [3,4-b] [1,3,4] THIADIAZOLES, s-TRIAZOLO [3,4-b] [1,3,4] THIADIAZINES AND s-TRIAZOLO [3′, 4′:2, 3]-THIADIAZINO [5,6-b] QUINOXALINE
Mohan, Jag
Rathee, Anju
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2011, 21 (02) : 117 - 120
[22] HETEROCYCLIC-SYSTEMS CONTAINING BRIDGEHEAD NITROGEN ATOM - SYNTHESIS AND ANTIMICROBIAL ACTIVITIES OF PARA-BIS(S-TRIAZOLO[3,4-B][1,3,4]THIADIAZIN-3-YL)PHENYLENE AND PARA-BIS(S-TRIAZOLO[3,4-B][1,3,4]THIADIAZOL-3-YL)PHENYLENE
MOHAN, J
ANJANEYULU, GSR
VERMA, P
CURRENT SCIENCE, 1989, 58 (18): : 1028 - 1030
[23] Bridgehead nitrogen heterocycles: Synthesis and biological activities of s-triazolo[3,4-b][1,3,4]thiadiazole system
Sudan, S
Gupta, R
Kachroo, PL
JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 1996, 73 (11) : 625 - 626
[24] HETEROCYCLIC-SYSTEMS CONTAINING BRIDGEHEAD NITROGEN ATOM - SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SYM-TRIAZOLO (3,4-B)(1,3,4)THIADIAZOLES, SYM-TRIAZOLO(3,4-B)(1,3,4)THIADIAZINES AND SYM-TRIAZOLO (3',4'-2,3)(1,3,4)THIADIAZINO(5,6-B)QUINOXALINE
MOHAN, J
ANJANEYULU, GSR
YAMINI, KVS
JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 1991, 68 (08) : 474 - 476
[25] HETEROCYCLIC-SYSTEMS CONTAINING BRIDGEHEAD NITROGEN ATOM .16. SYNTHESES OF S-TRIAZOLO[3,4-B] [I,3,4]THIADIAZINES AND RELATED HETEROCYCLES
DHAKA, KS
MOHAN, J
CHADHA, VK
PUJARI, HK
INDIAN JOURNAL OF CHEMISTRY, 1974, 12 (03): : 287 - 289
[26] Heterocyclic systems containing bridgehead nitrogen atom: Synthesis and bioactivity of 3-(1-adamantyl)-6-(p-chlorophenyl)-7H-s-triazolo[3,4-b][1,3,4]thiadiazine and 3,6-di-(1-adamantyl)-s-triazolo[3,4-b][1,3,4]thiadiazole
Mohan, J
Kataria, S
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 1995, 5 (02) : 143 - 144
[27] Synthesis and antibacterial activity of s-triazoles, s-triazolo[3,4-b]-1,3,4-thiadiazines and s-triazolo[3,4-b]-1,3,4-thiadiazoles of 5-methylisoxazole
Hui, XP
Zhang, LM
Zhang, ZY
Wang, Q
Wang, F
JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 2000, 47 (03) : 535 - 539
[28] Microwave assisted synthesis and bioactivity of s-triazolo[3,4-b][1,3,4] thiadiazoles, s-triazolo [3,4-b][1,3,4] thiadiazines and s-triazolo [3′,4′: 2,3]-thiadiazino[5,6-b] quinoxaline
Shiradkar, M
Shivaprasad, HN
ASIAN JOURNAL OF CHEMISTRY, 2006, 18 (01) : 319 - 324
[29] Novel Method for the Synthesis of s-Triazolo[3,4-b][1,3,4]thiadiazines
El-Sherief, Hassan A. H.
Hozien, Zeniab A.
El-Mahdy, Ahmed F. M.
Sarhan, Abdelwareth A. O.
SYNTHESIS-STUTTGART, 2010, (15): : 2636 - 2642
[30] 2,5-disubstituted s-triazolo[3,4-b] [1,3,4]thiadiazoles
Uher, M
Berkes, D
CHEMICAL PAPERS, 1999, 53 (03) : 215 - 217

← 1 2 3 4 5 →