Heterocyclic systems containing bridgehead nitrogen atom: Synthesis and bio-activity of imidazo [1,2-a]-s-triazolo [3,4-b][1,3,4]-thiadiazoles - A novel heterocyclic system

被引：0

作者：

Mohan, J ^{[1
]}

Kumar, V ^{[1
]}

Khattar, D ^{[1
]}

机构：

[1] Maharshi Dayanand Univ, Dept Chem, Rohtak 124001, Haryana, India

来源：

INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 1998年 / 8卷 / 01期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A facile synthesis of 7-aryl-3-n-propyl-imidazo [1,2-a]-s- triazolo [3,4-b][1,3,4]-thiadiazole (3) has been achieved by the condensation of 3-n-propyl-4-amino-5-propyl-s-triazole(1) with cyanogen bromide to yield 6-amino-3-propyl-s-triazolo [3,4-b]-[1,3,4]thiadiazole (2) followed by treatment with alpha-haloketones. The structures (3) were supported by IR and PMR spectral data. The antibacterial and antifungal activity of the system have also been evaluated.

引用

页码：73 / 74

页数：2

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