A novel and convenient method for synthesizing unsymmetrical N-benzyloxycarbonyl-protected 1-amino-1-arylalkylphosphonate mixed diesters

被引：31

作者：

Xu, JX ^{[1
]}

Fu, NY ^{[1
]}

机构：

[1] Peking Univ, Coll Chem & Mol Engn, Beijing 100871, Peoples R China

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 2001年 / 10期

关键词：

D O I：

10.1039/b008340m

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Unsymmetrical N-benzyloxycarbonyl-protected 1-amino-1-arylalkylphosphonate mixed diesters were synthesized using a one-pot reaction involving benzyl carbamate, aromatic aldehydes and alkoxydichlorophosphine, followed by treatment with alcohols in the presence of triethylamine. The reactions were followed by P-31 NMR and a mechanism is proposed.

引用

页码：1223 / 1226

页数：4

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