Impact of Right Ventricular Trabeculation on Right Ventricular Function in Patients With Left Ventricular Non-compaction Phenotype

被引:8
作者
Kiss, Anna Reka [1 ]
Gregor, Zsofia [1 ]
Popovics, Adrian [1 ]
Grebur, Kinga [1 ]
Szabo, Liliana Erzsebet [1 ]
Dohy, Zsofia [1 ]
Kovacs, Attila [1 ]
Lakatos, Balint Karoly [1 ]
Merkely, Bela [1 ]
Vago, Hajnalka [1 ]
Szucs, Andrea [1 ]
机构
[1] Semmelweis Univ, Heart & Vasc Ctr, Budapest, Hungary
来源
FRONTIERS IN CARDIOVASCULAR MEDICINE | 2022年 / 9卷
关键词
right ventricle (RV); right ventricular function; cardiac magnetic resonance (CMR); left ventricular non-compaction; non-comaption; trabecula; trabeculation; NONCOMPACTION; ADULTS; MYOCARDIUM; MASS;
D O I
10.3389/fcvm.2022.843952
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Right ventricular (RV) involvement in left ventricular (LV) non-compaction (LVNC) remains unknown. We aimed to describe the RV volumetric, functional, and strain characteristics and clinical features of patients with LVNC phenotype and good LV ejection fraction (EF) using cardiac magnetic resonance to characterize RV trabeculation in LVNC and to study the relationships of RV and LV trabeculation with RV volume and function. This retrospective study included 100 Caucasian patients with LVNC phenotype and good LV-EF and 100 age- and sex-matched healthy controls. Patients were further divided into two subgroups according to RV indexed trabecular mass [RV-TMi; patients with RV hypertrabeculation (RV-HT) vs. patients with normal RV trabeculation (RV-NT)]. We measured the LV and RV volumetric, functional, and TMi values using threshold-based postprocessing software and the RV and LV strain values using feature tracking and collected the patients' LVNC-related clinical features. Patients had higher RV volumes, lower RV-EF, and worse RV strain values than controls. A total of 22% of patients had RV-TMi values above the reference range; furthermore, RV-HT patients had higher RV and LV volumes, lower RV- and LV-EF, and worse RV strain values than RV-NT patients. We identified a strong positive correlation between RV- and LV-TMi and between RV-TMi and RV volumes and a significant inverse relationship of both RV- and LV-TMi with RV function. The prevalence of LVNC-related clinical features was similar in the RV-HT and RV-NT groups. These results suggest that some patients with LVNC phenotype might have RV non-compaction with subclinical RV dysfunction and without more severe clinical features.
引用
收藏
页数:10
相关论文
共 33 条
  • [1] Aggarwal Sourabh, 2016, Heart Views, V17, P30, DOI 10.4103/1995-705X.182645
  • [2] Myocardial strain imaging: review of general principles, validation, and sources of discrepancies
    Amzulescu, M. S.
    De Craene, M.
    Langet, H.
    Pasquet, A.
    Vancraeynest, D.
    Pouleur, A. C.
    Vanoverschelde, J. L.
    Gerber, B. L.
    [J]. EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING, 2019, 20 (06) : 605 - 619
  • [3] Reference values for left and right ventricular trabeculation and non-compacted myocardium
    Andre, Florian
    Burger, Astrid
    Lossnitzer, Dirk
    Buss, Sebastian J.
    Abdel-Aty, Hassan
    Gianntisis, Evangelos
    Steen, Henning
    Katus, Hugo A.
    [J]. INTERNATIONAL JOURNAL OF CARDIOLOGY, 2015, 185 : 240 - 247
  • [4] Clinical features of isolated ventricular noncompaction in adults long-term clinical course, echocardiographic properties, and predictors of left ventricular failure
    Aras, Dursun
    Tufekcioglu, Omac
    Ergun, Kumral
    Ozeke, Ozcan
    Yildiz, Ali
    Topaloglu, Serkan
    Deveci, Bulent
    Sahin, Onur
    Kisacik, Halil Lutfi
    Korkmaz, Sule
    [J]. JOURNAL OF CARDIAC FAILURE, 2006, 12 (09) : 726 - 733
  • [5] Sudden cardiac death in isolated right ventricular hypertrabeculation/noncompaction cardiomyopathy
    Bekheit, Soad
    Karam, Boutros
    Daneshvar, Farshid
    Zaidan, Julie
    Tabet, Rabih
    Spagnola, Jonathan
    Lafferty, James
    [J]. ANNALS OF NONINVASIVE ELECTROCARDIOLOGY, 2018, 23 (04)
  • [6] Right ventricle in heart failure with preserved ejection fraction
    Berglund, Felix
    Pina, Pamela
    Herrera, Cesar J.
    [J]. HEART, 2020, 106 (23) : 1798 - +
  • [7] Mortality and Sudden Death in Pediatric Left Ventricular Noncompaction in a Tertiary Referral Center
    Brescia, Samuel T.
    Rossano, Joseph W.
    Pignatelli, Ricardo
    Jefferies, John L.
    Price, Jack F.
    Decker, Jamie A.
    Denfield, Susan W.
    Dreyer, W. Jeffrey
    Smith, O'Brian
    Towbin, Jeffrey A.
    Kim, Jeffrey J.
    [J]. CIRCULATION, 2013, 127 (22) : 2202 - 2208
  • [8] Comparison of feature tracking, fast-SENC, and myocardial tagging for global and segmental left ventricular strain
    Bucius, Paulius
    Erley, Jennifer
    Tanacli, Radu
    Zieschang, Victoria
    Giusca, Sorin
    Korosoglou, Grigorious
    Steen, Henning
    Stehning, Christian
    Pieske, Burkert
    Pieske-Kraigher, Elisabeth
    Schuster, Andreas
    Lapinskas, Tomas
    Kelle, Sebastian
    [J]. ESC HEART FAILURE, 2020, 7 (02): : 523 - 532
  • [9] Analysis of right ventricular mass from magnetic resonance imaging data: a simple post-processing algorithm for correction of partial-volume effects
    Espe, Emil K. S.
    Bendiksen, Bard A.
    Zhang, Lili
    Sjaastad, Ivar
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2021, 320 (02): : H912 - H922
  • [10] Noncompaction of the Right Ventricle
    Fazio, Giovanni
    Lunetta, Monica
    Grassedonio, Emanuele
    Gullotti, Alessandro
    Ferro, Giovani
    Bacarella, Daniela
    Lo Re, Giuseppe
    Novo, Giuseppina
    Massimo, Midiri
    Maresi, Emiliano
    Novo, Salvatore
    [J]. PEDIATRIC CARDIOLOGY, 2010, 31 (04) : 576 - 578